Ouyang Yifei, He Mengjie, Zhang Limin, Chen Jihuai, Huang Fang, Cheng Yongbing, Zhang Bing
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Wei Sheng Yan Jiu. 2021 Jan;50(1):2-7. doi: 10.19813/j.cnki.weishengyanjiu.2021.01.002.
To analyze the relationship between different intensity of physical activity(PA) duration and cognitive function.
The 2018 Community-based Cohort Study on Nervous System Diseases used multi-stage stratified cluster randomization sampling method to select study participants. A total of 5571 participants aged 55 years and above from four provinces in China with complete information on demographic characteristics and PA and cognitive function were included in the final analysis. Basic information and PA data were collected by questionnaire. The Montreal cognitive assessment(MoCA) score method was adopted to evaluate the cognitive function. Light physical activity(LPA) duration and moderate-to-vigorous physical activity(MVPA) duration were calculated. Multivariate Logistic regression and Multiple linear regressions were used to analyze the relationship between different intensity of PA duration and the risk of mild cognitive impairment(MCI) and MoCA total score.
The median(P25, P75) of LPA and MVPA were 7. 0(0. 0, 16. 3) and 7. 3(0. 0, 14. 0) hours per week in the non-MCI group among 5571 participants aged 55 years and above in four provinces of China in 2018. In the MCI group, the median duration were 9. 3(0. 0, 17. 5) and 7. 0(0. 0, 11. 7) hours per week. The Logistic analysis showed that the OR of MCI was 0. 63(95%CI 0. 49-0. 82, P<0. 05) for the elderly with 3. 6-7. 0 hours of MVPA per week, compared to the elderly without MVPA. The OR of MCI was 1. 26(95%CI 0. 94-1. 67, P>0. 05) for the elderly with 3. 6-7. 0 hours of LPA per week compared to the elderly without LPA. Multiple linear regression analysis showed that compared to the elderly without MVPA, the total MoCA score increased with LPA duration increased as the duration was less than 10. 5 hours per week. The MoCA score decreased with LPA duration increased as duration was between 10. 5 and 21. 0 hours per week.
MVPA duration increment was associated with decreased prevalence of MCI and increased cognitive function in the elderly in four provinces of China. LPA duration should be maintained at an appropriate level in order to reduce the incidence of MCI and increased cognitive function in the elderly.
分析不同强度身体活动(PA)时长与认知功能之间的关系。
2018年基于社区的神经系统疾病队列研究采用多阶段分层整群随机抽样方法选取研究参与者。最终分析纳入了来自中国四个省份的5571名55岁及以上且具有完整人口统计学特征、PA及认知功能信息的参与者。通过问卷调查收集基本信息和PA数据。采用蒙特利尔认知评估(MoCA)评分法评估认知功能。计算轻度身体活动(LPA)时长和中度至剧烈身体活动(MVPA)时长。使用多因素Logistic回归和多元线性回归分析不同强度PA时长与轻度认知障碍(MCI)风险及MoCA总分之间的关系。
在2018年中国四个省份5571名55岁及以上参与者的非MCI组中,LPA和MVPA的中位数(P25,P75)分别为每周7.0(0.0,16.3)小时和7.3(0.0,14.0)小时。在MCI组中,中位数时长分别为每周9.3(0.0,17.5)小时和7.0(0.0,11.7)小时。Logistic分析显示,与无MVPA的老年人相比,每周MVPA时长为3.6 - 7.0小时的老年人发生MCI的OR为0.63(95%CI 0.49 - 0.82,P<0.05)。与无LPA的老年人相比,每周LPA时长为3.6 - 7.0小时的老年人发生MCI的OR为1.26(95%CI 0.94 - 1.67,P>0.05)。多元线性回归分析显示,与无MVPA的老年人相比,当LPA时长小于每周10.5小时时,MoCA总分随LPA时长增加而升高。当LPA时长在每周10.5至21.0小时之间时,MoCA评分随LPA时长增加而降低。
在中国四个省份的老年人中,MVPA时长增加与MCI患病率降低及认知功能增强相关。应将LPA时长维持在适当水平,以降低老年人MCI的发生率并增强认知功能。