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膳食模式和营养在非酒精性脂肪性肝病中的作用。

The Impact of Dietary Patterns and Nutrition in Nonalcoholic Fatty Liver Disease.

机构信息

Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

Gastroenterol Clin North Am. 2021 Mar;50(1):217-241. doi: 10.1016/j.gtc.2020.10.013.

Abstract

Nonalcoholic fatty liver disease (NAFLD) has become one of the most common causes of chronic liver disease worldwide. The prevalence of NAFLD has grown proportionally with the rise in obesity, sedentary lifestyle, unhealthy dietary patterns, and metabolic syndrome. Currently, in the absence of approved pharmacologic treatment, the keystone of treatment is lifestyle modification focused on achieving a weight loss of 7%-10%, cardiovascular exercise, and improving insulin sensitivity. The primary aim of this review is to outline the effect of different dietetic approaches against NAFLD and highlight the important micronutrient components in the management of NAFLD.

摘要

非酒精性脂肪性肝病(NAFLD)已成为全球最常见的慢性肝病病因之一。随着肥胖症、久坐不动的生活方式、不健康的饮食模式和代谢综合征的比例增加,NAFLD 的患病率也有所增加。目前,由于缺乏批准的药物治疗方法,治疗的重点是生活方式的改变,侧重于减轻 7%-10%的体重、进行心血管运动和提高胰岛素敏感性。本篇综述的主要目的是概述不同饮食方法对 NAFLD 的影响,并强调管理 NAFLD 中重要的微量营养素成分。

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