Valent Amy M, Barbour Linda A
Department of Obstetrics and Gynecology, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Mail Location L-458, Portland, OR 97239, USA.
Department of Medicine, University of Colorado Anschutz Medical Campus, 12801 East 17th Avenue, RC1 South Room 7103, Aurora, CO 80045, USA; Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, 12801 East 17th Avenue, RC1 South Room 7103, Aurora, CO 80045, USA.
Endocrinol Metab Clin North Am. 2021 Mar;50(1):57-69. doi: 10.1016/j.ecl.2020.10.005. Epub 2021 Jan 11.
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among reproductive age women and is associated with subfertility and adverse perinatal outcomes, which may include early pregnancy loss, gestational diabetes mellitus, hypertensive spectrum disorder, preterm birth, fetal growth disorders, and cesarean deliveries. The phenotypic heterogeneity, different diagnostic criteria, and PCOS-related conditions that women enter pregnancy with have limited evidenced-based studies and guidelines to reduce pregnancy complications among this high-risk population. This review summarizes the available evidence on the approach and management of women with PCOS preconception, prenatal, and postpartum.
多囊卵巢综合征（PCOS）是育龄女性中最常见的内分泌疾病，与生育力低下和不良围产期结局相关，这些结局可能包括早期妊娠丢失、妊娠期糖尿病、高血压谱系障碍、早产、胎儿生长发育障碍和剖宫产。PCOS的表型异质性、不同的诊断标准以及女性怀孕时伴随的PCOS相关情况，使得减少这一高危人群妊娠并发症的循证研究和指南有限。本综述总结了关于PCOS女性孕前、产前和产后处理及管理的现有证据。
