Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Japan.
Intern Med. 2021;60(3):373-378. doi: 10.2169/internalmedicine.5208-20. Epub 2021 Feb 1.
A 60-year-old man had received octreotide for a metastatic neuroendocrine tumor (NET) in the rectum. Computed tomography and ultrasonography revealed a cardiac tumor, diffuse thickness of the ventricular wall and pericardial effusion, which was diagnosed as cardiac metastasis. The metastatic lesions continued to grow despite the alteration of chemotherapy, and the patient complained of repeated syncope and was admitted to our hospital at 11 months after the diagnosis of cardiac metastasis. An electrocardiogram during syncope showed sustained ventricular tachycardia, which was considered to be caused by the cardiac metastasis. We herein report a case of NET with cardiac metastasis which caused lethal arrhythmia along with a review of the pertinent literature.
一位 60 岁男性因直肠转移性神经内分泌瘤(NET)而接受奥曲肽治疗。计算机断层扫描和超声检查显示心脏肿瘤、心室壁弥漫性增厚和心包积液,被诊断为心脏转移。尽管改变了化疗方案,但转移性病变仍继续生长,且患者反复出现晕厥,并在心脏转移诊断后 11 个月入住我院。晕厥期间的心电图显示持续性室性心动过速,考虑由心脏转移引起。我们在此报告一例 NET 伴心脏转移,导致致命性心律失常,并复习相关文献。