Chen Tong, Liu Dan, Yao Xiaofeng
Department of Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People's Republic of China.
Department of Preventive Medicine, Dalian Medical University, Dalian, Liaoning, People's Republic of China.
Diabetes Metab Syndr Obes. 2021 Jan 22;14:315-327. doi: 10.2147/DMSO.S290749. eCollection 2021.
Gestational diabetes mellitus (GDM) is one of the most common and severe complications of pregnancy, which is not only associated with perinatal complications but also has a long-term adverse effect on maternal and their offsprings. At present, the treatment of GDM focuses on the control of maternal blood glucose. Although lifestyle changes, hypoglycemic drugs, blood glucose monitoring, and other medicines that can improve maternal blood glucose to a certain extent, there are still some patients affected and have adverse pregnancy outcomes. The prevention of GDM and the treatment of improving pregnancy outcomes are urgently needed. This review summarized recently published clinical trials related with the treatment of GDM, aiming to provide additional options for the treatment of GDM.
妊娠期糖尿病(GDM)是妊娠最常见且严重的并发症之一,不仅与围产期并发症相关,还会对母亲及其后代产生长期不良影响。目前,GDM的治疗主要集中在控制母体血糖。尽管生活方式改变、降糖药物、血糖监测以及其他药物能在一定程度上改善母体血糖,但仍有部分患者受到影响并出现不良妊娠结局。因此,迫切需要预防GDM并改善妊娠结局。本综述总结了近期发表的与GDM治疗相关的临床试验,旨在为GDM的治疗提供更多选择。