无丝裂霉素C的经上皮光屈光性角膜切削术治疗飞秒激光原位角膜磨镶术角膜瓣并发症的效果
Effect of Transepithelial Photorefractive Keratectomy without Mitomycin C in the Treatment of Femtosecond Laser In Situ Keratomileusis Corneal Flap Complications.
作者信息
Wang Jing, Cao Weiqian, Tao Liming
机构信息
Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei 230601, China.
出版信息
J Ophthalmol. 2021 Jan 13;2021:8847922. doi: 10.1155/2021/8847922. eCollection 2021.
PURPOSE
To assess the efficacy and safety of transepithelial photorefractive keratectomy (TPRK) without mitomycin C as treatment for femtosecond laser in situ keratomileusis (FS-LASIK) corneal flap complications.
METHODS
Eight patients with corneal flap complications that occurred after FS-LASIK (five with eccentric flaps, two with buttonhole flaps, and one with a thick flap) were included in the study. Patients were treated with TPRK without mitomycin C between two weeks and twelve months after surgery. The postoperative manifest refraction, uncorrected distance visual acuity, and haze formation were assessed during six months of follow-up.
RESULTS
The mean manifest refractive spherical and cylinder refraction was 0.16 ± 0.26 and -0.44 ± 0.33 diopters, respectively, at six months postoperatively. The uncorrected distance visual acuity was above 20/25 in all patients after six months of follow-up. No haze formation was detected.
CONCLUSIONS
TPRK without mitomycin C appears to be a safe and effective treatment for FS-LASIK corneal flap complications.
目的
评估不使用丝裂霉素C的经上皮光性角膜切削术（TPRK）治疗飞秒激光原位角膜磨镶术（FS-LASIK）角膜瓣并发症的有效性和安全性。
方法
本研究纳入8例FS-LASIK术后出现角膜瓣并发症的患者（5例偏心瓣、2例纽扣孔瓣、1例厚瓣）。患者在术后2周和12个月之间接受了不使用丝裂霉素C的TPRK治疗。在6个月的随访期间评估术后明显验光、未矫正远视力和 haze形成情况。
结果
术后6个月时，平均明显验光球镜和柱镜屈光度分别为0.16±0.26和-0.44±0.33屈光度。随访6个月后，所有患者的未矫正远视力均高于20/25。未检测到haze形成。
结论
不使用丝裂霉素C的TPRK似乎是治疗FS-LASIK角膜瓣并发症的一种安全有效的方法。
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