Reim M, Müther H C, Karstens J H, Sieverts H
Abteilung Augenheilkunde, Medizinische Fakultät, Rheinisch-Westfälischen Technischen, Hochschule Aachen.
Klin Monbl Augenheilkd. 1988 Jan;192(1):33-6. doi: 10.1055/s-2008-1050068.
The authors present the case history of a child with neuroblastoma and early infiltration of the orbit accompanied by bilateral blindness. The typical clinical signs developed later. The thickening of the periosteum infiltrated by the tumor in the lateral wall of the orbit was demonstrated by computerized tomography. This may be regarded as an early sign of infiltration of the orbit by the neuroblastoma. In the case reported here a severe inflammatory reaction developed in the left orbit and anterior segment during massive chemotherapy and melted the cornea.
作者介绍了一名患有神经母细胞瘤且眼眶早期浸润并伴有双侧失明的儿童的病例史。典型的临床症状后来才出现。计算机断层扫描显示眼眶外侧壁被肿瘤浸润的骨膜增厚。这可被视为神经母细胞瘤眼眶浸润的早期迹象。在本文报道的病例中,在大规模化疗期间左眼眼眶和前段出现了严重的炎症反应,导致角膜溶解。