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多次复发后切口疝修复手术的结果:倾向评分匹配分析。

Outcomes of Incisional Hernia Repair Surgery After Multiple Re-recurrences: A Propensity Score Matched Analysis.

机构信息

Department of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Department of Surgery, IJsselland Ziekenhuis, Capelle aan den IJssel, The Netherlands.

出版信息

World J Surg. 2021 May;45(5):1425-1432. doi: 10.1007/s00268-021-05952-5. Epub 2021 Jan 31.

Abstract

BACKGROUND

Patients with a re-recurrent hernia may account for up to 20% of all incisional hernia (IH) patients. IH repair in this population may be complex due to an altered anatomical and biological situation as a result of previous procedures and outcomes of IH repair in this population have not been thoroughly assessed. This study aims to assess outcomes of IH repair by dedicated hernia surgeons in patients who have already had two or more re-recurrences.

METHODS

A propensity score matched analysis was performed using a registry-based, prospective cohort. Patients who underwent IH repair after ≥ 2 re-recurrences operated between 2011 and 2018 and who fulfilled 1 year follow-up visit were included. Patients with similar follow-up who underwent primary IH repair were propensity score matched (1:3) and served as control group. Patient baseline characteristics, surgical and functional outcomes were analyzed and compared between both groups.

RESULTS

Seventy-three patients operated on after ≥ 2 IH re-recurrences were matched to 219 patients undergoing primary IH repair. After propensity score matching, no significant differences in patient baseline characteristics were present between groups. The incidence of re-recurrence was similar between groups (≥ 2 re-recurrences: 25% versus control 24%, p = 0.811). The incidence of complications, as well as long-term pain, was similar between both groups.

CONCLUSION

IH repair in patients who have experienced multiple re-recurrences results in outcomes comparable to patients operated for a primary IH with a similar risk profile. Further surgery in patients who have already experienced multiple hernia re-recurrences is justifiable when performed by a dedicated hernia surgeon.

摘要

背景

再次复发疝的患者可能占所有切口疝 (IH) 患者的 20%。由于先前手术导致解剖和生物学情况发生改变,此类患者 IH 修复可能较为复杂,且此类患者 IH 修复的结果尚未得到全面评估。本研究旨在评估专门的疝外科医生对已经发生两次或以上复发的患者进行 IH 修复的结果。

方法

使用基于注册的前瞻性队列进行倾向评分匹配分析。纳入 2011 年至 2018 年期间接受过两次或以上复发 IH 修复且随访时间≥1 年的患者。选择具有相似随访时间且接受原发性 IH 修复的患者进行倾向评分匹配(1:3),作为对照组。分析并比较两组患者的基线特征、手术和功能结果。

结果

73 例接受两次或以上 IH 复发后手术的患者与 219 例接受原发性 IH 修复的患者进行了匹配。在进行倾向评分匹配后,两组患者的基线特征无显著差异。两组患者的复发率相似(≥两次复发:25%与对照组 24%,p=0.811)。两组患者的并发症发生率和长期疼痛相似。

结论

对于经历多次复发的患者,IH 修复的结果与接受原发性 IH 手术且风险特征相似的患者相当。当由专门的疝外科医生进行手术时,对于已经经历多次疝复发的患者,再次手术是合理的。

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