[肝脏常温机器灌注修复与评估系统的研发]

[Development of Liver Normothermic Machine Perfusion Repair and Assessment System].

作者信息

Liu Wenyan, Liu Fengfeng, Lyu Yi, Tang Bo, Ma Tao, Yan Yang, Zheng Yunqiao, Zheng Xinglong

机构信息

Department of Blood Purification, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061.

First Affiliated Hospital of Xi'an Jiaotong University, National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi'an, 710061.

出版信息

Zhongguo Yi Liao Qi Xie Za Zhi. 2021 Feb 8;45(1):37-41. doi: 10.3969/j.issn.1671-7104.2021.01.008.

DOI:10.3969/j.issn.1671-7104.2021.01.008

PMID:33522174

Abstract

This paper introduced a liver normothermic machine perfusion repair and assessment system. This system consists of a liver normothermic machine perfusion device, a fluorescence imaging system and a tissue oxygen detector. The normothermic machine perfusion device can continuously perfuse the donor liver and monitor and control the perfusion parameters in real time. The fluorescence imaging system can detect the indocyanine green metabolized by the liver to evaluate the microcirculation and the metabolism function of hepatocytes. The tissue oxygen detector can monitor the change of oxygen partial pressure of liver tissue in real time to evaluate the state of cell oxygen consumption.

摘要

本文介绍了一种肝脏常温机器灌注修复与评估系统。该系统由肝脏常温机器灌注装置、荧光成像系统和组织氧探测器组成。常温机器灌注装置可对供肝进行持续灌注，并实时监测和控制灌注参数。荧光成像系统可检测肝脏代谢的吲哚菁绿，以评估微循环和肝细胞的代谢功能。组织氧探测器可实时监测肝组织氧分压的变化，以评估细胞耗氧状态。