身体锻炼对减重手术患者的影响：一项随机对照临床试验方案。

Effect of physical exercise in bariatric surgery patients: protocol of a randomized controlled clinical trial.

机构信息

Department of Physical Medicine and Rehabilitation, San Juan de Dios Hospital, Curicó, Chile.

Laboratory of Clinical Research in Kinesiology, Department of Kinesiology, Universidad Católica del Maule, Talca, Chile.

出版信息

Trials. 2021 Feb 1;22(1):107. doi: 10.1186/s13063-021-05056-4.

DOI:10.1186/s13063-021-05056-4

PMID:33522950

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7849097/

Abstract

BACKGROUND

Bariatric surgery is an effective approach to weight loss and long-term comorbidity resolution. Although recommended in several guidelines, supervised exercise has not been systematically prescribed after bariatric surgery. The aim of this study is to determine the effects of two types of exercise, moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT), on body composition, cardiopulmonary function, and perceived quality of life in bariatric surgery patients.

METHODS

This randomized controlled exploratory pilot trial will include 75 adults of both sexes scheduled for bariatric surgery. They will be randomly assigned to one of three groups: (1) MICT, (2) HIIT, or (3) a control group. The intervention will occur 2 days a week for 4 months. Outcomes will be assessed at four points: (1) 1 week before surgery, (2) 21 days after surgery (baseline before the exercise program), (3) 8 weeks after beginning the exercise program, and (4) 1 week after the end of intervention. Primary outcomes will include body composition, heart rate variability, and 6-min walk test and quality of life scores. Secondary outcomes will be maximal respiratory pressure, flowmeter, hand dynamometry, and 30-s sit-to-stand test results.

DISCUSSION

Both exercise protocols in this study were developed according to evidence-based practice. It is expected that, after 16 weeks of intervention, body composition (measured by electrical bioimpedance), cardiopulmonary function (measured by heart rate variability, maximal inspiratory pressure, maximal expiratory pressure, peak expiratory flow, handgrip strength, and the 6-min walk test), and perceived quality of life (measured by the Moorehead-Ardelt quality of life questionnaire II and bariatric analysis and reporting outcome system scores) will improve, especially in the HIIT group.

TRIAL REGISTRATION

ClinicalTrials.gov NCT04235842 . Registered on 22 January 2020.

摘要

背景

减重手术是一种有效的减肥和长期解决合并症的方法。尽管在几项指南中都有推荐，但减重手术后并没有系统地规定监督运动。本研究的目的是确定两种类型的运动，即中等强度连续训练（MICT）和高强度间歇训练（HIIT），对减重手术患者的身体成分、心肺功能和感知生活质量的影响。

方法

这是一项随机对照探索性试点试验，将包括 75 名男女两性计划接受减重手术的成年人。他们将被随机分配到三个组之一：（1）MICT，（2）HIIT，或（3）对照组。干预将在每周 2 天进行，持续 4 个月。结果将在四个时间点进行评估：（1）手术前 1 周，（2）手术后 21 天（开始运动计划前的基线），（3）开始运动计划 8 周后，和（4）干预结束后 1 周。主要结果将包括身体成分、心率变异性和 6 分钟步行测试以及生活质量评分。次要结果将包括最大呼吸压力、流量计、手握力计和 30 秒坐立起身测试结果。

讨论

本研究中的两种运动方案都是根据循证实践制定的。预计在 16 周的干预后，身体成分（通过电阻抗测量）、心肺功能（通过心率变异性、最大吸气压力、最大呼气压力、呼气峰流速、手握力和 6 分钟步行测试测量）和感知生活质量（通过 Moorehead-Ardelt 生活质量问卷 II 和减重分析和报告结果系统评分测量）将得到改善，尤其是在 HIIT 组。