Harada A, D'Agostino H J, Boineau J P, Cox J L
Department of Surgery, Washington University School of Medicine, Barnes Hospital, St. Louis, MO 63110.
J Thorac Cardiovasc Surg. 1988 Apr;95(4):651-7.
Surgical isolation of the body of the right atrium presents a unique hemodynamic situation in which the synchronous right atrial contraction (kick) is lost but the synchronous left atrial contraction is preserved. The hemodynamic effects of this procedure were evaluated by pacing at selected atrial sites postoperatively to simulate (1) sinus rhythm with a synchronous right atrial kick, (2) sinus rhythm without a synchronous right atrial kick, (3) right atrial tachycardia propagated to the entire heart (propagated right atrial tachycardia), and (4) right atrial tachycardia confined to the isolated right atrium with sinus rhythm in the rest of the heart (confined right atrial tachycardia). Hemodynamic data recorded under these four conditions showed that (1) during sinus rhythm, synchrony of right atrial contraction had no significant effect on any of the hemodynamic parameters studied and (2) conversion from propagated right atrial tachycardia to confined right atrial tachycardia resulted in an increase in mean arterial pressure (65 +/- 5 to 78 +/- 3 mm Hg, p less than 0.005) and stroke volume index (9 +/- 1 to 19 +/- 3 ml/beat/m2, p less than 0.005) with a decrease in left atrial pressure (9 +/- 2 to 5 +/- 1 mm Hg, p less than 0.05) and right atrial pressure (6 +/- 1 to 5 +/- 1 mm Hg, p less than 0.05). Moreover, cardiac hemodynamic performance remained within normal limits for up to 14 weeks. Thus the right atrial isolation procedure does not adversely affect cardiac hemodynamics despite the loss of synchronous right atrial contraction during sinus rhythm, and the procedure prevents hemodynamic deterioration during right atrial tachycardia.
右心房体部的手术隔离呈现出一种独特的血流动力学情况,即右心房同步收缩(搏动)丧失,但左心房同步收缩得以保留。通过术后在选定的心房部位进行起搏来评估该手术的血流动力学效应,以模拟(1)具有同步右心房搏动的窦性心律,(2)无同步右心房搏动的窦性心律,(3)传播至整个心脏的右房性心动过速(传播性右房性心动过速),以及(4)局限于孤立右心房且心脏其余部分为窦性心律的右房性心动过速(局限性右房性心动过速)。在这四种情况下记录的血流动力学数据表明,(1)在窦性心律期间,右心房收缩的同步性对所研究的任何血流动力学参数均无显著影响,并且(2)从传播性右房性心动过速转变为局限性右房性心动过速会导致平均动脉压升高(65±5至78±3 mmHg,p<0.005)和每搏量指数增加(9±1至19±3 ml/beat/m2,p<0.005),同时左心房压力降低(9±2至5±1 mmHg,p<0.05)和右心房压力降低(6±1至5±1 mmHg,p<0.05)。此外,心脏血流动力学性能在长达14周内保持在正常范围内。因此,尽管在窦性心律期间右心房同步收缩丧失,但右心房隔离手术不会对心脏血流动力学产生不利影响,并且该手术可防止右房性心动过速期间的血流动力学恶化。