Barat M, Rybak L P, Dietrich J
Department of Surgery, Southern Illinois University, Springfield.
Laryngoscope. 1988 Apr;98(4):418-21. doi: 10.1288/00005537-198804000-00013.
Malignant thymoma is a mediastinal tumor which spreads primarily by local invasion. Spread to regional lymph nodes and distant organs is variable. The most common sites of metastasis in the head and neck region are the supraclavicular nodes and the brain. Cervical lymph node metastasis as the presenting symptom of malignant thymoma has not yet been reported in the otolaryngologic literature. We present three cases of metastatic thymoma to the neck from a series of 28 thymomas, ten of which were malignant. The clinical presentation, histopathological features, therapy, and prognosis of malignant thymomas are discussed.
恶性胸腺瘤是一种主要通过局部浸润扩散的纵隔肿瘤。扩散至区域淋巴结和远处器官的情况各不相同。头颈部区域最常见的转移部位是锁骨上淋巴结和脑。恶性胸腺瘤以颈部淋巴结转移为首发症状在耳鼻喉科文献中尚未见报道。我们从28例胸腺瘤（其中10例为恶性）中呈现3例颈部转移性胸腺瘤病例。并对恶性胸腺瘤的临床表现、组织病理学特征、治疗及预后进行了讨论。
