MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, United Kingdom.
Imperial Prostate, Division of Surgery, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom; Imperial Urology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Urology. 2021 Sep;155:1-8. doi: 10.1016/j.urology.2021.01.035. Epub 2021 Jan 29.
To determine the effect of prostate biopsy on erectile function we conducted a systematic review and meta-analysis up to August 2020. Mean difference of International Index of Erectile Function-5 compared to baseline scores were pooled at 1, 3 and 6-months using a random effect model. Of 47 full text articles identified, 7 were included in the meta-analysis. A significant reduction in mean IIEF5 of 4.61 (0.32-8.91, P= .04) was found at 1-month post biopsy. This resolved with non-significant differences at 3- and 6-months post procedure. Patients should be counselled regarding the transient effect on erectile function post biopsy.
为了确定前列腺活检对勃起功能的影响，我们进行了系统评价和荟萃分析，截至 2020 年 8 月。使用随机效应模型，在 1、3 和 6 个月时对与基线评分相比的国际勃起功能指数-5 的平均差异进行了汇总。在确定的 47 篇全文文章中，有 7 篇被纳入荟萃分析。在活检后 1 个月时发现平均 IIEF5 显著降低 4.61（0.32-8.91，P=.04）。在 3 个月和 6 个月时，差异没有统计学意义。应告知患者关于活检后勃起功能的短暂影响。
