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结直肠癌筛查:单中心经验

Colorectal cancer screenings: a single center experience.

作者信息

Viani Lorenzo, Dell'Abate Paolo, Del Rio Paolo, Marchesi Federico, Tartamella Francesco, Rossini Matteo, Bertocchi Elisa, Giuffrida Mario

机构信息

Dipartimento di Scienze Chirurgiche, sezione di Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi di Parma, Parma, Italy..

Dipartimento di Medicina e Chirurgia, sezione di Clinica Chirurgica Generale , Università degli Studi di Parma, Via Gramsci n.14, 43100 Parma Italia..

出版信息

Acta Biomed. 2020 Nov 10;91(4):e2020101. doi: 10.23750/abm.v91i4.8386.

Abstract

AIM

evaluating the impact of screening programmes on colorectal cancer (CRC) in Italy.

METHODS

we studied 1292 patients with colorectal cancer. Data were collected from January 2004 through December 2015 in Parma University Hospital. We compared clinophatological features to evaluate the real impact of screening programmes on detecting early stage colorectal cancers in target population.

RESULTS

screening programmes with fecal occult blood test (FOBT) and colonoscopy covered only patients from 50 to 69. In our study we reported that the 52,3% of patients with CRC were over 70 and out of screen time, while only 47,7% were under 70. Early detection seems to be related to early stage of CRC and to an improved overall survival.

CONCLUSION

The importance of early detection in colorectal cancers represents the most important outcome for OS. The risk of colorectal cancer is increased in elderly. Actual screening programmes cover less than 50% of population with colorectal cancer. Screening should be considered for patients over 70, due to the high number of new diagnosis in symptomatic disease and worst prognosis, in accordance with advanced cancer stage and comorbidities in elderly.

摘要

目的

评估筛查项目对意大利结直肠癌(CRC)的影响。

方法

我们研究了1292例结直肠癌患者。数据于2004年1月至2015年12月在帕尔马大学医院收集。我们比较临床病理特征以评估筛查项目对在目标人群中检测早期结直肠癌的实际影响。

结果

粪便潜血试验(FOBT)和结肠镜检查的筛查项目仅覆盖50至69岁的患者。在我们的研究中,我们报告称52.3%的CRC患者年龄超过70岁且不在筛查时间范围内,而只有47.7%的患者年龄在70岁以下。早期检测似乎与CRC的早期阶段以及总体生存率的提高有关。

结论

结直肠癌早期检测的重要性是总体生存率的最重要结果。老年人患结直肠癌的风险增加。实际的筛查项目覆盖不到50%的结直肠癌患者。鉴于有症状疾病的新诊断数量众多且预后较差,以及老年人癌症晚期和合并症的情况,应考虑对70岁以上的患者进行筛查。

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