以培尼单抗治疗全身性幼年特发性关节炎伴发心包炎 1 例
Perimyocarditis as first sign of systemic onset juvenile idiopathic arthritis treated successfully with anakinra: a case-based review.
机构信息
Array.
Pediatric Rheumatology Unit, Santa Maria Nuova Hospital, Reggio Emilia, Italy.
出版信息
Acta Biomed. 2020 Sep 15;91(4):ahead of print. doi: 10.23750/abm.v91i4.9093.
Abstract
BACKGROUND
The involvement of myocardium and pericardium at the same time is very uncommon as first manifestation of juvenile idiopathic arthritis with systemic onset (soJIA).
CASE
A fourteen years-old boy, referred with symptoms of acute gastroenteritis, developed a perimyocarditis as first manifestation of Still's Disease, after only one day from the admission. The rheumatologic disease was not responding to glucocorticoid treatment. The use of anakinra was the key point of the therapy and after its administration the patient started to recover fastly.
CONCLUSIONS
This case report describes cardiac involvement as first sign of soJIA and the successful use of anakinra inducing remission of soJIA not-responding to steroid therapy.
摘要
背景
心肌和心包同时受累作为全身型幼年特发性关节炎（soJIA）的首发表现非常罕见。
病例
一名 14 岁男孩，因急性胃肠炎就诊，入院仅一天后即出现心肌炎，表现为斯蒂尔病。该风湿性疾病对糖皮质激素治疗无反应。使用阿那白滞素是治疗的关键，使用后患者开始迅速恢复。
结论
本病例报告描述了心脏受累作为 soJIA 的首发表现，以及阿那白滞素的成功应用诱导了对激素治疗无反应的 soJIA 缓解。
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