Verdeguer A, Castel V, Torres V, Olagüe R, Ferris J, Esquembre C, Vallcanera A, Muro M D
Department of Pediatric Oncology, Hospital Infantil La Fe, Valencia, Spain.
Med Pediatr Oncol. 1988;16(2):98-100. doi: 10.1002/mpo.2950160206.
Results of 70 fine-needle aspiration biopsies (FNAB) were evaluated retrospectively in 61 pediatric patients. Over a period of 9 months all mass lesions suspected being malignant were aspirated. Twelve of the 70 aspirations were performed in children having known tumours, in order to exclude recurrence or metastasis. The others were carried out to obtain a diagnosis. Satisfactory specimens were obtained from 58 (83%). There were 21 benign diagnoses, 36 malignant diagnoses, and 1 with suspected malignancy. Correlation of histologic and cytologic diagnoses was possible in 45 cases. The diagnostic sensitivity and specificity were 95% and 80%, respectively. We have found FNAB more accurate in the diagnosis of malignancies than in benign lesions. The results suggest that this is a useful technique for obtaining a first diagnosis of malignancy, as well as for excluding recurrence or metastatic disease.
回顾性评估了61例儿科患者70次细针穿刺活检（FNAB）的结果。在9个月的时间里，对所有疑似恶性的肿块病变进行了抽吸。70次抽吸中有12次是在已知患有肿瘤的儿童中进行的，以排除复发或转移。其他抽吸是为了获得诊断。58例（83%）获得了满意的标本。有21例良性诊断，36例恶性诊断，1例疑似恶性。45例病例的组织学和细胞学诊断具有相关性。诊断敏感性和特异性分别为95%和80%。我们发现FNAB在恶性肿瘤诊断中比在良性病变中更准确。结果表明，这是一种获得恶性肿瘤初步诊断以及排除复发或转移性疾病的有用技术。
