Giorgetti Arianna, Orazietti Vasco, Busardò Francesco Paolo, Pirani Filippo, Giorgetti Raffaele
Department of Medical and Surgical Sciences, Unit of Legal Medicine, University of Bologna, Via Irnerio 49, 40126 Bologna, Italy.
Department of Excellence of Biomedical Sciences and Public Health, University "Politecnica delle Marche" of Ancona, via Conca 71, 60126 Ancona, Italy.
Diagnostics (Basel). 2021 Jan 28;11(2):190. doi: 10.3390/diagnostics11020190.
Since December 2019, a new form of coronavirus, SARS-CoV-2, has spread from China to the whole word, raising concerns regarding Coronavirus Disease 2019 (COVID-19) endangering public health and life. Over 1.5 million deaths related with COVID-19 have been recorded worldwide, with wide variations among countries affected by the pandemic and continuously growing numbers. The aim of this paper was to provide an overview of the literature cases of deaths involving COVID-19 and to evaluate the application of the COVID-19 Significance Score (CSS) in the classification of SARS CoV-2-related fatalities, comparing it with the Hamburg rating scale. The results obtained allowed us to highlight that CSS used after a complete accurate post-mortem examination, coupled to the retrieval of in vivo data, post-mortem radiology, histology and toxicology, as well as to additional required analyses (e.g., electronic microscopy) is a useful and concise tool in the assessment of the cause of death and the role played by this virus. A shared use of this scale might hopefully lower the inhomogeneities in forensic evaluation of SARS CoV-2-related fatalities.
自2019年12月以来，一种新型冠状病毒——严重急性呼吸综合征冠状病毒2（SARS-CoV-2）已从中国传播至全球，引发了对2019冠状病毒病（COVID-19）危及公众健康和生命的担忧。全球已记录了超过150万例与COVID-19相关的死亡病例，在受该疫情影响的国家中差异很大，且数量持续增长。本文的目的是概述涉及COVID-19的死亡病例文献，并评估COVID-19重要性评分（CSS）在SARS-CoV-2相关死亡病例分类中的应用，将其与汉堡评分量表进行比较。所得结果使我们能够强调，在进行完整准确的尸检后使用CSS，并结合体内数据、尸检放射学、组织学和毒理学以及其他所需分析（如电子显微镜检查），是评估死亡原因以及该病毒所起作用的一种有用且简洁的工具。共同使用该量表有望降低SARS-CoV-2相关死亡病例法医评估中的不均匀性。
