Columbia University Irving Medical Center, Department of Internal Medicine, New York, NY.
Duke Cancer Institute, Durham, NC.
Cleve Clin J Med. 2021 Feb 1;88(2):117-127. doi: 10.3949/ccjm.88a.19148.
Recent developments in precision oncology have increased the complexity of diagnostic and therapeutic decisions. Here, we broadly review the field of precision oncology and discuss common mutational drivers in non-small cell lung cancer (NSCLC) that directly relate to the diagnosis, evaluation, and treatment of patients with metastatic disease.
精准肿瘤学的最新进展增加了诊断和治疗决策的复杂性。在这里,我们广泛回顾了精准肿瘤学领域,并讨论了非小细胞肺癌(NSCLC)中常见的突变驱动因素,这些因素直接与转移性疾病患者的诊断、评估和治疗相关。