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城乡 40 岁及以上居民糖尿病现状及差异:来自 2017-2019 年中国东北地区一项基于人群的研究。

Status and disparities of diabetes among urban and rural residents aged 40 years and older: insight from a population-based study in northeast China, 2017-2019.

机构信息

Department of Cardiology, The First Hospital of China Medical University, Shenyang, Liaoning, China.

Department of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, Liaoning, China.

出版信息

J Epidemiol Community Health. 2021 Aug;75(8):800-808. doi: 10.1136/jech-2020-213755. Epub 2021 Feb 1.

Abstract

OBJECTIVES

To evaluate the up-to-date epidemiology of diabetes in northeast China.

METHODS

The cross-sectional study was conducted between September 2017 and March 2019 using a multistage, stratified and cluster random sampling method. 18 796 participants (28.9% urban and 71.1% rural) aged ≥40 years were enrolled. Diabetes and pre-diabetes were diagnosed according to the history, fasting plasma glucose (FPG) and glycosylated haemoglobin A1c (HbA1c) levels.

RESULTS

The prevalence of diabetes was 17.1%, higher in urban than in rural residents (20.2% vs 15.8%, p<0.001). Meanwhile, the prevalence of pre-diabetes was 44.3%, higher in rural than in urban areas (49.4% vs 31.8%, p<0.001). The overall FPG and HbA1c were 6.10±1.94 mmol/L and 5.59%±1.08%. The FPG level was higher in rural area than in urban areas (6.15±1.83 mmol/L vs 5.97±2.18 mmol/L, p<0.001). Among participants with diabetes, 47.5% were aware of their diabetes condition; 39.5% were taking antidiabetic medications and 36.8% of people had their diabetes controlled. The awareness and treatment rates in rural areas were lower than those in urban areas (47.3% vs 57.5%, 34.4% vs 49.5%, p<0.001). Patients with diabetic, especially those in rural areas, tended to have multiple risk factors including hypertension (71.7%), overweight or obesity (69.6%) and dyslipidaemia (52.8%).

CONCLUSION

A considerable burden of diabetes was observed in northeast China, with high percentage of untreated diabetes, high prevalence of pre-diabetes, high overall FPG level and multiple uncontrolled risk factors in patients with diabetics. Therefore, region-specific strategies on prevention and management of diabetes should be emphasised.

摘要

目的

评估中国东北地区糖尿病的最新流行病学情况。

方法

本横断面研究于 2017 年 9 月至 2019 年 3 月采用多阶段、分层和整群随机抽样方法进行。共纳入 18796 名年龄≥40 岁的参与者(28.9%为城市居民,71.1%为农村居民)。根据病史、空腹血糖(FPG)和糖化血红蛋白 A1c(HbA1c)水平诊断糖尿病和糖尿病前期。

结果

糖尿病患病率为 17.1%,城市居民高于农村居民(20.2%比 15.8%,p<0.001)。同时,糖尿病前期患病率为 44.3%,农村居民高于城市居民(49.4%比 31.8%,p<0.001)。总体 FPG 和 HbA1c 分别为 6.10±1.94mmol/L 和 5.59%±1.08%。农村地区 FPG 水平高于城市地区(6.15±1.83mmol/L 比 5.97±2.18mmol/L,p<0.001)。在糖尿病患者中,47.5%知晓自己的糖尿病病情;39.5%正在服用降糖药物,36.8%的患者血糖得到控制。农村地区的知晓率和治疗率均低于城市地区(47.3%比 57.5%,34.4%比 49.5%,p<0.001)。糖尿病患者,尤其是农村地区的患者,往往存在多种危险因素,包括高血压(71.7%)、超重或肥胖(69.6%)和血脂异常(52.8%)。

结论

中国东北地区糖尿病负担较重,未治疗的糖尿病比例较高,糖尿病前期患病率较高,糖尿病患者总体 FPG 水平较高,且多种危险因素未得到控制。因此,应强调针对该地区的糖尿病预防和管理策略。

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