Faculty of Veterinary Medicine, Latvia University of Life Sciences and Technologies, Jelgava, Latvia.
Faculty of Medicine, University of Tartu, Tartu, Estonia.
Anat Histol Embryol. 2021 May;50(3):550-555. doi: 10.1111/ahe.12660. Epub 2021 Feb 1.
Studies on localization and distribution of enteroendocrine cells (EECs) are important for better understanding of their role in the ontogenetic development of intestines. Information about the distribution of the most important endocrine cells in the digestive tract of the ostrich is very limited; therefore, the aim of the present study was to identify gastrin and somatostatin EECs in the small intestine of the ostrich (Struthio camelus var. domesticus) chicks at different ages. Six embryos along with 42 ostriches of both sexes from hatching up to 60 days post-hatching, including six embryos, were obtained from an ostrich farm in Latvia. Duodenum, jejunum and ileum were investigated using routine histology and immunohistochemistry methods. Gastrin and somatostatin EECs were examined in 10 microscopic fields of the intestinal mucosa in each tissue sample. The cells were detected in all age groups as well as the embryos. The number of both types of EEC in the mucosa of the ileum was significantly lower (p < .01-.05) than in the duodenum. The present study suggested that the EEC may have a role in the development of the mucosa of the intestinal tract of ostriches with possible involvement in the development of the digestive functions.
肠内分泌细胞（EECs）的定位和分布研究对于更好地了解其在肠道发生发育中的作用非常重要。关于鸵鸟消化道中最重要的内分泌细胞分布的信息非常有限；因此，本研究旨在确定不同年龄鸵鸟（Struthio camelus var. domesticus）雏鸡小肠中的胃泌素和生长抑素 EECs。从拉脱维亚的一个鸵鸟养殖场获得了六个胚胎和 42 只不同性别从孵化到孵化后 60 天的鸵鸟。使用常规组织学和免疫组织化学方法研究了十二指肠、空肠和回肠。在每个组织样本的 10 个肠黏膜显微镜视野中检查胃泌素和生长抑素 EECs。在所有年龄组和胚胎中均检测到这两种类型的 EEC。回肠黏膜中这两种类型的 EEC 数量明显低于十二指肠（p <.01-.05）。本研究表明，EEC 可能在鸵鸟肠道黏膜的发育中发挥作用，可能参与消化功能的发育。
