Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University, Seoul, Korea.
Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.
Vet Med Sci. 2021 May;7(3):642-646. doi: 10.1002/vms3.441. Epub 2021 Feb 1.
This study was performed to evaluate the effect of intra-abdominal pressure (IAP) on intraocular pressure (IOP) in conscious dog models using a balloon technique to generate intra-abdominal hypertension. Six healthy dogs without ocular abnormalities were evaluated in this study. A balloon device was placed in the intra-abdominal cavity. The abdomen was insufflated to IAP levels of 15 and 25 mmHg using the balloon device. Intraocular pressure was measured at baseline, at IAP levels of 15 and 25 mmHg, and after decompression. In comparison with the mean baseline IOP (15.1 ± 2.0 mmHg), there was a significant increase in IOP at IAP levels of 15 mmHg (20.0 ± 2.1 mmHg) and 25 mmHg (19.9 ± 2.2 mmHg), corresponding to a 32.4% and 31.7% increase from baseline IOP, respectively. The mean IOP after decompression (14.8 ± 1.7 mmHg) was significantly lower compared to those at IAP levels of 15 and 25 mmHg. The present findings demonstrate that increased IAP has a clinically significant effect on IOP in dogs under conscious conditions. Although more research is needed to determine of increased IAP on IOP, these findings suggest that increased IAP leads to mild and reversible increase in IOP.
本研究采用球囊技术产生腹腔内高压，评估了腹腔内压力（IAP）对清醒犬模型眼内压（IOP）的影响。本研究评估了 6 只无眼部异常的健康犬。将球囊装置置于腹腔内。使用球囊装置将腹部充气至 IAP 水平 15 和 25mmHg。在基线、IAP 水平 15 和 25mmHg 以及减压后测量眼内压。与平均基线 IOP（15.1±2.0mmHg）相比，IAP 水平为 15mmHg（20.0±2.1mmHg）和 25mmHg（19.9±2.2mmHg）时IOP 显著升高，分别比基线IOP 升高 32.4%和 31.7%。减压后平均 IOP（14.8±1.7mmHg）明显低于 IAP 水平为 15 和 25mmHg 时的 IOP。本研究结果表明，在清醒状态下，升高的 IAP 对犬的 IOP 有显著的临床影响。尽管需要进一步研究以确定升高的 IAP 对 IOP 的影响，但这些发现表明升高的 IAP 导致 IOP 轻度且可逆升高。
