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针对立法的单专科术后阿片类药物处方模式变化:随时间的单机构分析。

Changes in Single-Specialty Postoperative Opioid Prescribing Patterns in Response to Legislation: Single-Institution Analysis Over Time.

机构信息

Department of Otolaryngology, Miller School of Medicine, The University of Miami, Miami, Florida, USA.

Department of Neurological Surgery, Miller School of Medicine, The University of Miami, Miami, Florida, USA.

出版信息

Otolaryngol Head Neck Surg. 2021 Apr;164(4):774-780. doi: 10.1177/0194599820986577. Epub 2021 Feb 2.

Abstract

OBJECTIVES

To determine changes in the prescriptions of postoperative opioids in response to Florida state legislation restricting the number of days for which these medications could be prescribed to 3 days in most circumstances or 7 days at provider discretion.

STUDY DESIGN

A retrospective review was performed for all patients undergoing 7 common outpatient otolaryngology surgical procedures.

SETTING

Single-institution academic center in Florida.

METHODS

Query of the state's online prescription drug monitoring program was used to compare prescription habits 3 months before and after the law and then again 1 year later.

RESULTS

A total of 561 patients were identified meeting criteria. The number of days that opioids were prescribed decreased significantly, from 6.42 to 4.48 to 3.03 days. There was a significant decrease in the proportion of patients receiving any postoperative opioid prescription, from 0.80 to 0.52 to 0.32. The total morphine milligram equivalents prescribed decreased from 28.4 before the law to 18.4 at 1 year after.

CONCLUSIONS

Legislative restrictions on the length of opioid prescriptions were associated with significant decreases in the proportion of patients receiving any opioids, the number of days that opioids were prescribed, and the total morphine milligram equivalents 3 months after the law went into effect, with even more dramatic changes at the 1-year time point. We opine that these changes are due to providers learning that many procedures do not require postoperative opioids and therefore increasingly considering and utilizing nonopioid alternatives in this setting.

摘要

目的

确定术后阿片类药物处方的变化,以响应佛罗里达州的立法,将这些药物的处方天数限制在大多数情况下的 3 天,或在提供者自行决定的情况下的 7 天。

研究设计

对所有接受 7 种常见耳鼻喉科门诊手术的患者进行回顾性研究。

地点

佛罗里达州的一家单一机构学术中心。

方法

查询该州的在线处方药物监测计划,以比较该法律生效前 3 个月、生效后 1 年的处方习惯。

结果

共确定了 561 名符合条件的患者。阿片类药物的处方天数显著减少,从 6.42 天减少到 4.48 天,再减少到 3.03 天。接受任何术后阿片类药物处方的患者比例显著下降,从 0.80 下降到 0.52,再下降到 0.32。处方的总吗啡毫克当量从法律生效前的 28.4 毫克减少到 1 年后的 18.4 毫克。

结论

对阿片类药物处方长度的立法限制与接受任何阿片类药物的患者比例、阿片类药物的处方天数以及法律生效后 3 个月的总吗啡毫克当量显著减少相关,在 1 年的时间点上,变化更为显著。我们认为,这些变化是由于提供者了解到许多手术不需要术后阿片类药物,因此在这种情况下越来越多地考虑和使用非阿片类替代药物。

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