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中央脊髓损伤:磁共振成像确诊及手术考量

Central spinal cord injury: magnetic resonance imaging confirmation and operative considerations.

作者信息

Fox J L, Wener L, Drennan D C, Manz H J, Won D J, Al-Mefty O

机构信息

Division of Neurosurgery, Georgetown University Medical Center, Washington, District of Columbia.

出版信息

Neurosurgery. 1988 Feb;22(2):340-7. doi: 10.1227/00006123-198802000-00011.

Abstract

A case of central cervical spinal cord injury, confirmed by magnetic resonance imaging (MRI) and treated by myelotomy, is presented. After recovering well from his central cord syndrome and walking with assistance, the patient developed a rapidly progressive myelopathy beginning 2 months after injury. His main injury localized clinically to the C8, T1 level; but central cord abnormalities were identified 3 months after injury at the C6 level by MRI: a high signal intensity on the proton density sequence and a low-signal intensity on the T1-weighted sequence. At operation 41/2 months after his injury and 1 month after complete paraplegia, a myelotomy at C6 failed to reveal any cavity (syrinx) but instead disclosed only intense gliosis inside a slightly atrophic spinal cord. Rapid clinical improvement ensued. Secondary syringomyelia may be an endstage condition after spinal cord insults that trigger a progressive, pathophysiological reaction leading to central cord necrosis. In selected cases, myelotomy may interrupt this MRI-identified, nosogenic process before cavitation has occurred.

摘要

本文介绍了一例经磁共振成像(MRI)确诊并接受脊髓切开术治疗的颈髓中央损伤病例。患者从中央脊髓综合征中恢复良好并在辅助下行走,但在受伤2个月后出现快速进展的脊髓病。其主要损伤在临床上定位于C8、T1水平;但受伤3个月后通过MRI在C6水平发现中央脊髓异常:质子密度序列上呈高信号强度,T1加权序列上呈低信号强度。在受伤4个半月且完全截瘫1个月后进行手术,C6水平的脊髓切开术未发现任何空洞(脊髓空洞症),而是仅在轻度萎缩的脊髓内发现严重的胶质增生。随后临床迅速改善。继发性脊髓空洞症可能是脊髓损伤后的终末期状况,这种损伤引发了导致中央脊髓坏死的进行性病理生理反应。在某些选定病例中,脊髓切开术可能在空洞形成之前中断这种经MRI识别的致病过程。

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