Oncology Institute "Prof. Dr. Ion Chiricuţă", Cluj-Napoca, Romania.
Doctoral School, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Dis Markers. 2021 Jan 19;2021:6653971. doi: 10.1155/2021/6653971. eCollection 2021.
When a cardiologist is asked to evaluate the cardiac toxic effects of chemotherapy, he/she can use several tools: ECG, echocardiography, coronary angiography, ventriculography, and cardiac MRI. Of all these, the fastest and easiest to use is the ECG, which can provide information on the occurrence of cardiac toxic effects and can show early signs of subclinical cardiac damage. These warning signs are the most desired to be recognized by the cardiologist, because the dose of chemotherapeutics can be adjusted so that the clinical side effects do not occur, or the therapy can be stopped in time, before irreversible side effects. This review addresses the problem of early detection of cardiotoxicity in adult and pediatric cancer treatment, by using simple ECG recordings.
当心脏病专家被要求评估化疗的心脏毒性作用时，他/她可以使用几种工具：心电图、超声心动图、冠状动脉造影、心室造影和心脏 MRI。在所有这些工具中，最快、最容易使用的是心电图，它可以提供心脏毒性作用发生的信息，并显示亚临床心脏损伤的早期迹象。这些警告信号是心脏病专家最希望识别的，因为可以调整化疗药物的剂量，从而避免发生临床副作用，或者在不可逆的副作用发生之前及时停止治疗。本综述通过使用简单的心电图记录来探讨在成人和儿科癌症治疗中心肌毒性的早期检测问题。
