Centre for Research On Environmental Ecology and Fish Nutrient of the Ministry of Agriculture, Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai, 201306, China.
College of Fisheries and Life Science, Shanghai Ocean University, Shanghai, 201306, China.
Arch Environ Contam Toxicol. 2021 Feb;80(2):402-413. doi: 10.1007/s00244-021-00811-9. Epub 2021 Feb 3.
In this study, we assessed the effects of 11-day exposure of sulfadiazine (SD), sulfamethazine (SM2), norfloxacin (NOR), and enrofloxacin (ENR) on the growth, chlorophyll a (Chl. a) content, phycobiliproteins (PBPs) content, and alkaline phosphatase (ALP) activity of Chrysosporum ovalisporum, examined the removal rate of these antibiotics by C. ovalisporum, and performed acute toxicology test with Daphnia magna to determine the effect of interaction between antibiotics and cyanobacteria on aquatic animals. The results showed that the stress of SD and SM2 increased extracellular ALP activity and weakly inhibited the algal growth and the contents of Chl. a and PBPs compared with that noted in the control. ENR and NOR treatment groups exerted significant inhibition on algal growth as well as Chl. a and PBPs contents and ALP activity, although the cyanobacterium could degrade these two antibiotics more than SD and SM2. The results also revealed that the interaction between antibiotics and cyanobacteria could inhibit D. magna feeding.
在这项研究中，我们评估了磺胺嘧啶（SD）、磺胺甲噁唑（SM2）、诺氟沙星（NOR）和恩诺沙星（ENR）连续 11 天暴露对卵形隐藻生长、叶绿素 a（Chl. a）含量、藻胆蛋白（PBPs）含量和碱性磷酸酶（ALP）活性的影响，研究了卵形隐藻对这些抗生素的去除率，并采用大型溞进行急性毒理学试验，以确定抗生素与蓝藻相互作用对水生动物的影响。结果表明，与对照组相比，SD 和 SM2 的应激增加了胞外 ALP 活性，并对藻类生长以及 Chl. a 和 PBPs 的含量有微弱的抑制作用。ENR 和 NOR 处理组对藻类生长以及 Chl. a 和 PBPs 的含量和 ALP 活性均有显著抑制作用，尽管蓝藻对这两种抗生素的降解能力强于 SD 和 SM2。结果还表明，抗生素与蓝藻的相互作用会抑制大型溞摄食。
