Duhault J, Regnault F
Paroi Arterielle. 1977 Jun;4(1):7-25.
Diabetic microangiopathy is a degenerative process specific to diabetes. Metabolic theory holds that the metabolic defect predisposes to vascular abnormalities, but other theory suggests that microangiopathy and metabolic disorders are of different origin. Metabolic and ultrastructural modifications in kidney and retina are reviewed. Human and animal studies suggest a specific organ response to fortuitous association of several factors leading to microvascular disease.
糖尿病微血管病变是糖尿病特有的一种退行性病变过程。代谢理论认为,代谢缺陷易引发血管异常,但其他理论则表明微血管病变和代谢紊乱起源不同。本文综述了肾脏和视网膜的代谢及超微结构改变。人体和动物研究表明,特定器官对多种导致微血管疾病的因素偶然关联会产生特异性反应。