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[纳米技术在骨科与创伤学中抗生素输送方面的应用]

[Nanotechnology applied to the transport of antibiotics in orthopedics and traumatology].

作者信息

Cancela-Vila N

机构信息

Instituto Nacional de Ortopedia y Traumatología (INOT). Montevideo, Uruguay.

出版信息

Acta Ortop Mex. 2020 Jul-Aug;34(4):249-253.

Abstract

Bone infection and implants are a real problem in orthopedics. The formation of biofilm as well as multi-existing pathogens to antibiotics, make fighting them a difficult challenge with the tools we have today. With the aim of knowing the current state of nanotechnology applied to the transport of antibiotics in traumatology and orthopedics, and their projection in the future. We conducted a bibliographic review in June 2019. While much development of the topic and work on humans is lacking, experimental studies show that nanotechnology applied to antibiotic transport promises to be an important weapon in the treatment of bone infections in the future.

摘要

骨感染和植入物是骨科领域的一个实际问题。生物膜的形成以及对抗生素存在多种耐药病原体,使得利用我们现有的工具对抗它们成为一项艰巨的挑战。为了了解纳米技术在创伤学和骨科领域应用于抗生素输送的现状及其未来发展前景,我们于2019年6月进行了一次文献综述。虽然该主题的很多进展以及针对人类的研究尚显不足,但实验研究表明,应用于抗生素输送的纳米技术有望成为未来治疗骨感染的一项重要武器。

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