Bukhari Muhammad A
From the Division of Nephrology, Department of Medicine, Taif University, Taif, Saudi Arabia.
Exp Clin Transplant. 2022 May;20(5):500-513. doi: 10.6002/ect.2020.0180. Epub 2021 Feb 1.
The number of patients with organ failure in Saudi Arabia is increasing annually, and transplantation offers the best outcome for these patients. However, the number of donors does not meet these needs.
A questionnaire was distri-buted to assess the behavior of participants in Saudi Arabia toward different types of organ donation. The questionnaire examined general willingness to donate, deceased donation, living donation, and refusal to donate, as well as paired-exchange donation and next-of-kin consenting.
Of the 1099 participants, most were men (64%) and middle-aged (46%, 31-45 years old), with 36% of participants currently willing to donate or already registered as donors. Although 592 participants (54%) were not yet willing to donate, they believed they could consider making donations in specific circumstances (eg, when a relative is in need). In all circumstances, 10% (n = 108) of the participants refused to donate. With regard to deceased donation, 74% of participants accepted this, but only 29% (n = 322) agreed to consent for donation as next of kin. Of 1099 participants, 143 (13%) were willing to accept altruistic donation. Paired-exchange donation was widely accepted in a cohort study (n = 725, 65%), as opposed to list exchange (n = 540, 49%). Religious beliefs were the main reason behind the refusal of donation in the study cohort (n = 37, 37%). Female participants were less likely to refuse organ donation (odds ratio: 0.562; 95% CI, 0.407-0.775; P < .001), whereas older participants (> 60 years) were more likely to refuse organ donation (odds ratio: 5.457; 95% CI, 1.894-15.722; P = .002).
This study described the willingness of the Saudi population to donate organs in general and under special conditions, such as deceased donation, living-unrelated donation, altruistic donation, paired-exchange donation, list exchange donation, and next-of-kin consent.
沙特阿拉伯器官衰竭患者的数量逐年增加,而移植为这些患者提供了最佳治疗效果。然而,捐赠者的数量无法满足这些需求。
发放一份问卷,以评估沙特阿拉伯参与者对不同类型器官捐赠的态度。该问卷调查了一般捐赠意愿、死后捐赠、活体捐赠、拒绝捐赠,以及配对交换捐赠和近亲同意捐赠的情况。
在1099名参与者中,大多数为男性(64%)且为中年(46%,年龄在31至45岁之间),36%的参与者目前愿意捐赠或已登记为捐赠者。尽管592名参与者(54%)尚未愿意捐赠,但他们认为在特定情况下(如亲属有需要时)可以考虑捐赠。在所有情况下,10%(n = 108)的参与者拒绝捐赠。关于死后捐赠,74%的参与者接受,但只有29%(n = 322)同意作为近亲同意捐赠。在1099名参与者中,143名(13%)愿意接受利他性捐赠。在一项队列研究中,配对交换捐赠被广泛接受(n = 725,65%),而列表交换则不然(n = 540,49%)。宗教信仰是研究队列中拒绝捐赠的主要原因(n = 37,37%)。女性参与者拒绝器官捐赠的可能性较小(优势比:0.562;95%置信区间,0.4 <.001),而年龄较大的参与者(> 60岁)拒绝器官捐赠的可能性较大(优势比:5.457;95%置信区间,1.894至15.722;P =.002)。
本研究描述了沙特民众在一般情况下以及在特殊条件下(如死后捐赠、非亲属活体捐赠、利他性捐赠、配对交换捐赠、列表交换捐赠和近亲同意捐赠)捐赠器官的意愿。