Department of Pediatrics, Harvard Medical School, Harvard University, Boston, Massachusetts; and
Division of Emergency Medicine and.
Hosp Pediatr. 2021 Mar;11(3):277-283. doi: 10.1542/hpeds.2020-000315. Epub 2021 Feb 3.
Children with deep neck infections (DNIs) are increasingly being managed nonsurgically with intravenous antibiotics. Our objective was to examine variation in the management of children with DNIs across US children's hospitals.
We conducted a retrospective cohort study using the Pediatric Health Information System database. Children ≤12 years of age hospitalized for retropharyngeal or parapharyngeal abscesses from 2010 to 2018 were included. Hospital variation in management modality and imaging use was described. Temporal trends in management modality were assessed by using logistic regression. Medical management alone versus a combination of medical and surgical management was assessed, and the characteristics of children in these 2 groups were compared. The relationship between hospital rates of initial medical management and failed medical management was assessed by using linear regression.
Hospitals varied widely in their rates of surgical management from 17% to 70%. The overall rate of surgical management decreased from 42.0% to 33.5% over the study period. Children managed surgically had higher rates of ICU admission (11.5% vs 3.2%; < .001) and higher hospital charges ($25 241 vs $15 088; < .001) compared with those managed medically alone. Seventy-three percent of children underwent initial medical management, of whom 17.9% went on to undergo surgery. Hospitals with higher rates of initial medical management had lower rates of failed medical management (β = -.43).
Although rates of surgical management of pediatric DNI are decreasing over time, there remains considerable variation in management across US children's hospitals. Children managed surgically have higher rates of resource use and costs.
越来越多患有深部颈部感染(DNI)的儿童采用静脉内抗生素进行非手术治疗。我们的目的是研究美国儿童医院对患有 DNI 的儿童的管理方法存在的差异。
我们使用儿科健康信息系统数据库进行了回顾性队列研究。纳入 2010 年至 2018 年因咽后或咽旁脓肿住院的≤12 岁儿童。描述了管理方式和影像学应用的医院差异。采用逻辑回归评估管理方式的时间趋势。评估了单纯药物治疗与药物联合手术治疗的效果,并比较了这两组儿童的特征。通过线性回归评估医院初始药物治疗成功率与失败率之间的关系。
医院手术治疗率差异很大,从 17%到 70%不等。在研究期间,手术治疗的总体比率从 42.0%降至 33.5%。与单纯药物治疗相比,手术治疗的儿童 ICU 入住率(11.5% vs. 3.2%;<0.001)和住院费用($25241 vs. $15088;<0.001)更高。73%的儿童接受了初始药物治疗,其中 17.9%的儿童接受了手术。初始药物治疗率较高的医院,其药物治疗失败率较低(β=-0.43)。
尽管小儿 DNI 的手术治疗率随着时间的推移呈下降趋势,但美国儿童医院的管理方法仍存在很大差异。手术治疗的儿童资源利用率和成本更高。