• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

观点对垒:临床微生物实验室是否应该报告万古霉素 MIC 结果?

Point-Counterpoint: Should Clinical Microbiology Laboratories Report Vancomycin MICs?

机构信息

Medical College of Wisconsin, School of Pharmacy, Milwaukee, Wisconsin, USA

Virginia Commonwealth University Health System, Richmond, Virginia, USA

出版信息

J Clin Microbiol. 2021 Mar 19;59(4). doi: 10.1128/JCM.00239-21.

DOI:10.1128/JCM.00239-21
PMID:33536296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8092730/
Abstract

INTRODUCTIONWith numerous reported challenges to reporting MICs for vancomycin, clinical laboratories are attempting to identify accurate methods for MIC testing. However, the issues of poor reproducibility, accuracy, and clinical utility remain a challenge. In this Point-Counterpoint, Dr. Sara Revolinski discusses the pros of reporting MICs for vancomycin, while Dr. Christopher Doern argues for the use of caution.

摘要

引言

由于报告万古霉素 MIC 值存在众多报道的挑战,临床实验室正在试图确定 MIC 检测的准确方法。然而,重现性差、准确性和临床实用性等问题仍然是一个挑战。在这篇观点对立方文章中,Sara Revolinski 博士讨论了报告万古霉素 MIC 值的优点,而 Christopher Doern 博士则对其使用提出了谨慎意见。

相似文献

1
Point-Counterpoint: Should Clinical Microbiology Laboratories Report Vancomycin MICs?观点对垒:临床微生物实验室是否应该报告万古霉素 MIC 结果?
J Clin Microbiol. 2021 Mar 19;59(4). doi: 10.1128/JCM.00239-21.
2
Vancomycin MICs do not predict the outcome of methicillin-resistant Staphylococcus aureus bloodstream infections in correctly treated patients.万古霉素最低抑菌浓度并不能预测接受正确治疗的耐甲氧西林金黄色葡萄球菌血流感染患者的治疗结果。
J Antimicrob Chemother. 2012 Jul;67(7):1760-8. doi: 10.1093/jac/dks128. Epub 2012 May 3.
3
Use of daptomycin to treat infections with methicillin-resistant Staphylococcus aureus isolates having vancomycin minimum inhibitory concentrations of 1.5 to 2 μg/mL.使用达托霉素治疗对万古霉素最低抑菌浓度为1.5至2μg/mL的耐甲氧西林金黄色葡萄球菌分离株引起的感染。
Ann Pharmacother. 2013 Dec;47(12):1654-65. doi: 10.1177/1060028013508272. Epub 2013 Nov 1.
4
High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus.万古霉素和达托霉素的高最低抑菌浓度以及耐甲氧西林金黄色葡萄球菌引起的复杂导管相关血流感染
Emerg Infect Dis. 2016 Jun;22(6):1057-66. doi: 10.3201/eid2206.151709.
5
Vancomycin minimum inhibitory concentrations (MICs) for meticillin-resistant Staphylococcus aureus (MRSA) in Hong Kong.香港耐甲氧西林金黄色葡萄球菌(MRSA)的万古霉素最低抑菌浓度(MICs)
Int J Antimicrob Agents. 2010 Oct;36(4):386-7. doi: 10.1016/j.ijantimicag.2010.06.039. Epub 2010 Aug 11.
6
Impact of vancomycin MIC creep on patients with methicillin-resistant Staphylococcus aureus bacteremia.万古霉素 MIC 漂移对耐甲氧西林金黄色葡萄球菌菌血症患者的影响。
J Microbiol Immunol Infect. 2012 Jun;45(3):214-20. doi: 10.1016/j.jmii.2011.11.006. Epub 2012 May 7.
7
Occurrence of vancomycin MIC creep in methicillin resistant isolates in Saudi Arabia.沙特阿拉伯耐甲氧西林金黄色葡萄球菌中万古霉素 MIC 缓慢升高的发生。
J Infect Public Health. 2020 Oct;13(10):1576-1579. doi: 10.1016/j.jiph.2020.07.008. Epub 2020 Aug 25.
8
More accurate measurement of vancomycin minimum inhibitory concentration indicates poor outcomes in meticillin-resistant Staphylococcus aureus bacteraemia.更准确地测量万古霉素最低抑菌浓度表明耐甲氧西林金黄色葡萄球菌菌血症的预后不良。
Int J Antimicrob Agents. 2015 Nov;46(5):532-7. doi: 10.1016/j.ijantimicag.2015.07.013. Epub 2015 Aug 31.
9
Vancomycin MIC as a predictor of outcome in MRSA bacteraemia in the UK context.万古霉素 MIC 作为英国耐甲氧西林金黄色葡萄球菌菌血症患者预后的预测指标。
J Antimicrob Chemother. 2013 Nov;68(11):2641-7. doi: 10.1093/jac/dkt234. Epub 2013 Jun 21.
10
Comparison of method-specific vancomycin minimum inhibitory concentration values and their predictability for treatment outcome of meticillin-resistant Staphylococcus aureus (MRSA) infections.特定方法的万古霉素最低抑菌浓度值比较及其对耐甲氧西林金黄色葡萄球菌(MRSA)感染治疗结果的预测性
Int J Antimicrob Agents. 2008 Nov;32(5):378-85. doi: 10.1016/j.ijantimicag.2008.05.007. Epub 2008 Aug 12.

引用本文的文献

1
Standardized Treatment and Assessment Pathway Improves Mortality in Adults With Methicillin-resistant Bacteremia: STAPH Study.标准化治疗与评估路径改善耐甲氧西林菌血症成人患者的死亡率:葡萄球菌研究
Open Forum Infect Dis. 2021 May 23;8(7):ofab261. doi: 10.1093/ofid/ofab261. eCollection 2021 Jul.

本文引用的文献

1
Twenty-Year Trends in Antimicrobial Susceptibilities Among From the SENTRY Antimicrobial Surveillance Program.哨兵抗菌监测计划中20年的抗菌药物敏感性趋势。 需注意,你提供的原文“Twenty-Year Trends in Antimicrobial Susceptibilities Among From the SENTRY Antimicrobial Surveillance Program.”表述似乎不太完整,“Among”后面缺少具体内容。以上译文是基于现有内容尽量准确翻译的。
Open Forum Infect Dis. 2019 Mar 15;6(Suppl 1):S47-S53. doi: 10.1093/ofid/ofy270. eCollection 2019 Mar.
2
Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia.达托霉素联合头孢洛林与标准护理单药治疗耐甲氧西林金黄色葡萄球菌菌血症的临床数据。
Antimicrob Agents Chemother. 2019 Apr 25;63(5). doi: 10.1128/AAC.02483-18. Print 2019 May.
3
Conversion from Vancomycin Trough Concentration-Guided Dosing to Area Under the Curve-Guided Dosing Using Two Sample Measurements in Adults: Implementation at an Academic Medical Center.从基于万古霉素谷浓度的给药方案转换为基于曲线下面积的给药方案:在成人中使用两次样本测量的实施。
Pharmacotherapy. 2019 Apr;39(4):433-442. doi: 10.1002/phar.2234. Epub 2019 Mar 18.
4
Making the change to area under the curve-based vancomycin dosing.改为基于曲线下面积的万古霉素给药方案。
Am J Health Syst Pharm. 2018 Dec 15;75(24):1986-1995. doi: 10.2146/ajhp180034. Epub 2018 Oct 17.
5
Prospective Trial on the Use of Trough Concentration versus Area under the Curve To Determine Therapeutic Vancomycin Dosing.前瞻性研究使用谷浓度与曲线下面积来确定治疗万古霉素剂量。
Antimicrob Agents Chemother. 2018 Jan 25;62(2). doi: 10.1128/AAC.02042-17. Print 2018 Feb.
6
A Quasi-Experiment To Study the Impact of Vancomycin Area under the Concentration-Time Curve-Guided Dosing on Vancomycin-Associated Nephrotoxicity.一项研究万古霉素浓度时间曲线下面积指导给药对万古霉素相关性肾毒性影响的准实验研究。
Antimicrob Agents Chemother. 2017 Nov 22;61(12). doi: 10.1128/AAC.01293-17. Print 2017 Dec.
7
Relationship between vancomycin exposure and outcomes among patients with MRSA bloodstream infections with vancomycin Etest® MIC values of 1.5mg/L: A pilot study.万古霉素Etest® MIC值为1.5mg/L的耐甲氧西林金黄色葡萄球菌血流感染患者中万古霉素暴露与预后的关系:一项初步研究。
Diagn Microbiol Infect Dis. 2017 Jul;88(3):259-263. doi: 10.1016/j.diagmicrobio.2017.03.008. Epub 2017 Apr 2.
8
AUC/MIC Pharmacodynamic Target Is Not a Good Predictor of Vancomycin Efficacy in Methicillin-Resistant Staphylococcus aureus Experimental Endocarditis.AUC/MIC药效学靶点并非耐甲氧西林金黄色葡萄球菌实验性心内膜炎中万古霉素疗效的良好预测指标。
Antimicrob Agents Chemother. 2017 May 24;61(6). doi: 10.1128/AAC.02486-16. Print 2017 Jun.
9
Ceftaroline fosamil monotherapy for methicillin-resistant Staphylococcus aureus bacteremia: a comparative clinical outcomes study.头孢洛林酯单药治疗耐甲氧西林金黄色葡萄球菌菌血症:一项比较临床结局研究。
Int J Infect Dis. 2017 Apr;57:27-31. doi: 10.1016/j.ijid.2017.01.019. Epub 2017 Jan 25.
10
Discrepancy in Vancomycin AUC/MIC Ratio Targeted Attainment Based upon the Susceptibility Testing in Staphylococcus aureus.基于金黄色葡萄球菌药敏试验的万古霉素AUC/MIC比值目标达成情况的差异
Antibiotics (Basel). 2016 Sep 27;5(4):34. doi: 10.3390/antibiotics5040034.