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骶神经调节在大便失禁治疗中的现状

Current Position of Sacral Neuromodulation in Treatment of Fecal Incontinence.

作者信息

Katuwal Binit, Bhullar Jasneet

机构信息

Department of Surgery, Providence Hospital & Medical Centers, Southfield, Michigan.

Department of Surgery, UPMC Williamsport, Williamsport, Pennsylvania.

出版信息

Clin Colon Rectal Surg. 2021 Jan;34(1):22-27. doi: 10.1055/s-0040-1714247. Epub 2021 Jan 28.

Abstract

Fecal incontinence (FI) is defined as uncontrolled passage of feces or gas for at least 1-month duration in an individual who previously had control. FI is a common and debilitating condition affecting many individuals. Continence depends on complex relationships between anal sphincters, rectal curvatures, rectoanal sensation, rectal compliance, stool consistency, and neurologic function. Factors, such as pregnancy, chronic diarrhea, diabetes mellitus, previous anorectal surgery, urinary incontinence, smoking, obesity, limited physical activity, white race, and neurologic disease, are known to be the risk factors for FI. Conservative/medical management including biofeedback are recognized as the first-line treatment of the FI. Those who are suitable for surgical intervention and who have failed conservative management, sacral nerve stimulation (SNS) has emerged as the treatment of choice in many patients. The surgical technique involves placement of a tined lead with four electrodes through the S3 sacral foramen. The lead is attached to a battery, which acts as a pulse generator, and is placed under the patient's skin in the lower lumbar region. The use of SNS in the treatment of FI has increased over the years and the beneficial effects of this treatment have been substantiated by multiple studies. This review describes SNS as a modality of treatment for FI and its position in the current medical diaspora in patients with FI.

摘要

大便失禁(FI)被定义为在既往有控制能力的个体中,粪便或气体不受控制地排出至少持续1个月。FI是一种影响许多人的常见且使人衰弱的病症。控便取决于肛门括约肌、直肠弯曲、直肠肛管感觉、直肠顺应性、粪便稠度和神经功能之间的复杂关系。已知诸如怀孕、慢性腹泻、糖尿病、既往肛肠手术、尿失禁、吸烟、肥胖、身体活动受限、白种人和神经疾病等因素是FI的危险因素。包括生物反馈在内的保守/药物治疗被公认为是FI的一线治疗方法。对于那些适合手术干预且保守治疗失败的患者,骶神经刺激(SNS)已成为许多患者的首选治疗方法。手术技术包括通过S3骶孔放置一根带有四个电极的带倒刺导线。该导线连接到一个电池,该电池充当脉冲发生器,并放置在患者下腰部的皮肤下。多年来,SNS在FI治疗中的应用有所增加,多项研究证实了这种治疗的有益效果。本综述将SNS描述为FI的一种治疗方式及其在当前FI患者医学领域中的地位。

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Current Position of Sacral Neuromodulation in Treatment of Fecal Incontinence.骶神经调节在大便失禁治疗中的现状
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本文引用的文献

1
Pathophysiology and Therapeutic Options for Fecal Incontinence.大便失禁的病理生理学及治疗选择
J Clin Gastroenterol. 2017 Apr;51(4):324-330. doi: 10.1097/MCG.0000000000000797.
7
The epidemiology of anal incontinence and symptom severity scoring.肛门失禁的流行病学和症状严重程度评分。
Gastroenterol Rep (Oxf). 2014 May;2(2):79-84. doi: 10.1093/gastro/gou005. Epub 2014 Feb 27.

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