Nooner Kate B, Chung Tammy, Feldstein Ewing Sarah W, Brumback Ty, Arwood Zjanya, Tapert Susan F, Brown Sandra A, Cottler Linda
Department of Psychology, The University of North Carolina at Wilmington, Wilmington, NC, United States.
Department of Psychiatry, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States.
Front Behav Neurosci. 2021 Jan 18;14:597902. doi: 10.3389/fnbeh.2020.597902. eCollection 2020.
The novel coronavirus pandemic that emerged in late 2019 (COVID-19) has created challenges not previously experienced in human research. This paper discusses two large-scale NIH-funded multi-site longitudinal studies of adolescents and young adults - the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) and the Adolescent Brain Cognitive Development (ABCD) Study - and valuable approaches to learn about adaptive processes for conducting developmentally sensitive research with neuroimaging and neurocognitive testing across consortia during a global pandemic. We focus on challenges experienced during the pandemic and modifications that may guide other projects, such as implementing adapted protocols that protect the safety of participants and research staff, and addressing assessment challenges through the use of strategies such as remote and mobile assessments. Given the pandemic's disproportionate impacts on participants typically underrepresented in research, we describe efforts to retain these individuals. The pandemic provides an opportunity to develop adaptive processes that can facilitate future studies' ability to mobilize effectively and rapidly.
2019年末出现的新型冠状病毒大流行（COVID-19）给人类研究带来了前所未有的挑战。本文讨论了两项由美国国立卫生研究院资助的针对青少年和青年的大规模多地点纵向研究——青少年酒精与神经发育国家联盟（NCANDA）和青少年大脑认知发展（ABCD）研究——以及在全球大流行期间，通过神经影像学和神经认知测试，跨联盟开展对发育敏感的研究，以了解适应过程的宝贵方法。我们关注大流行期间遇到的挑战以及可能指导其他项目的调整措施，例如实施保护参与者和研究人员安全的适应性方案，以及通过使用远程和移动评估等策略应对评估挑战。鉴于大流行对研究中通常代表性不足的参与者产生了不成比例的影响，我们描述了为留住这些个体所做的努力。大流行提供了一个机会，来开发适应性过程，以促进未来研究有效且迅速地调动资源的能力。
