Prakash Ramachandran Loganathan Mohan, Hwang Du Hyeon, Hong Il-Hwa, Chae Jinho, Kang Changkeun, Kim Euikyung
College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.
Institute of Animal Medicine, Gyeongsang National University, Jinju 52828, Korea.
Data Brief. 2021 Jan 8;34:106721. doi: 10.1016/j.dib.2021.106721. eCollection 2021 Feb.
This article reports data associated with Prakash et al. [1]. Nemopilema nomurai jellyfish venom (NnV) can lead to neurotoxicity in zebrafish (Danio rerio) model In the present study, zebrafish were treated with NnV by intraperitoneal injection and the swimming behavior of each fish was evaluated using a score scale. The dose of NnV in each treatment group was based on the protein concentration of NnV. Swimming is the main locomotory movements in the fishes. NnV modulated the swimming behavior of in a dose-dependent manner. In this article provided data are directly related to the previously published research article - " as an alternative vertebrate model for jellyfish venom study: the toxinological aspects of venom" [1] where the downregulation of acetylcholinesterase activity as well as histopathological alterations were observed from the brain of treated with NnV. Here we provide datasets, including mortality rate table, swimming behavior graph, and videos of zebrafish after NnV envenomation.
本文报道了与普拉卡什等人[1]相关的数据。野村水母毒液（NnV）可导致斑马鱼（Danio rerio）模型出现神经毒性。在本研究中，通过腹腔注射用NnV处理斑马鱼，并使用评分量表评估每条鱼的游泳行为。每个处理组中NnV的剂量基于NnV的蛋白质浓度。游泳是鱼类主要的运动方式。NnV以剂量依赖的方式调节斑马鱼的游泳行为。本文提供的数据与之前发表的研究文章“作为水母毒液研究的替代脊椎动物模型：野村水母毒液的毒理学方面”[1]直接相关，在该研究中观察到用NnV处理的斑马鱼大脑中乙酰胆碱酯酶活性下调以及组织病理学改变。在此我们提供数据集，包括死亡率表、游泳行为图以及NnV中毒后斑马鱼的视频。
