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迁移与发病率:对疾病地理学研究的启示

Migration and morbidity: implications for geographical studies of disease.

作者信息

Bentham G

机构信息

School of Environmental Sciences, University of East Anglia, Norwich, England.

出版信息

Soc Sci Med. 1988;26(1):49-54. doi: 10.1016/0277-9536(88)90044-5.

Abstract

Many studies have examined associations between the geographical patterns of disease and possible causal factors. Underlying such studies is the assumption that residence in an area can be equated with exposure to conditions that pertain there. Migration upsets this assumption. Using data on self-reported morbidity from the 1981 Census for Great Britain it is shown that the health status of migrants differs considerably from that of non-migrants. Young migrants, particularly those moving longer distances are relatively healthy. Area of net out-migration of this age group are therefore likely to become characterised by a less healthy population whereas the reverse will be true of areas of net in-migration. Amongst older people migration tends to be selective of those in poor health moving shorter distances to avoid environmental health hazards or to be closer to medical care. This has the curious effect of increasing morbidity and mortality rates in areas with favourable environmental conditions and good medical services. Migration is therefore likely to be a significant source of error in geographically based studies of the association between disease and the environment. Sometimes the effect will be to obscure real environmental causes of disease. In other circumstances spurious association will be produced. These problems will be greatest for diseases with long latent periods which allow plenty of time for mobility of the population. Problems are also likely to increase with the growing mobility of the population.

摘要

许多研究都探讨了疾病的地理分布模式与可能的致病因素之间的关联。这些研究的潜在假设是,居住在某个地区等同于暴露于该地区存在的各种条件之下。而移民打破了这一假设。利用1981年英国人口普查中关于自我报告发病率的数据表明,移民的健康状况与非移民有很大差异。年轻移民,尤其是那些迁移距离较长的移民,相对较为健康。因此,这个年龄段的净迁出地区可能会出现人口健康状况较差的特征,而净迁入地区则情况相反。在老年人中,移民往往选择健康状况较差的人,他们迁移较短的距离以避免环境卫生危害或更靠近医疗服务。这就产生了一种奇特的效果,即在环境条件良好且医疗服务完善的地区,发病率和死亡率会上升。因此,在基于地理因素对疾病与环境之间关联的研究中,移民很可能是一个重大的误差来源。有时这种影响会掩盖疾病真正的环境成因。在其他情况下,则会产生虚假关联。对于潜伏期较长的疾病,这些问题最为严重,因为这类疾病有足够的时间让人口流动。随着人口流动性的不断增加,问题也可能会加剧。

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