Kim Seung-Hyun, Behnes Michael, Akin Ibrahim
I. Medizinische Klinik, Universitätsmedizin Mannheim (UMM), Medizinische Fakultät Mannheim, Universität Heidelberg, DZHK (Deutsches Zentrum für Herzkreislaufforschung), Partner-Site Heidelberg/Mannheim.
Ther Umsch. 2021 Feb;78(1):2-10. doi: 10.1024/0040-5930/a001230.
Strategy for Chronic Coronary Syndrome - PCI or optimal medical therapy In the new guidelines of the European Society of Cardiology (ESC), the previous term "stable coronary artery disease (CAD)" was replaced by a new term "chronic coronary syndrome (CCS)" in order to highlight the chronic but also progressive pathological character of CAD. Both optimal medical therapy and myocardial revascularization play a central role in the treatment of patients with CCS. However, due to the heterogeneity of CCS, it is a challenge to determine in clinical practice which patients may benefit from percutaneous coronary intervention (PCI). In addition, the importance of PCI is still controversial, especially in patients with CCS. Hence, this review discusses diagnostic and therapeutic approaches in patients with CCS considering the current ESC-guidelines and the ISCHEMIA Trial (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) in order to outline the optimal strategy for improving symptoms and prognosis.
慢性冠状动脉综合征的治疗策略——PCI还是最佳药物治疗 在欧洲心脏病学会(ESC)的新指南中,先前的术语“稳定型冠状动脉疾病(CAD)”被新术语“慢性冠状动脉综合征(CCS)”所取代,以突出CAD的慢性但也具有进展性的病理特征。最佳药物治疗和心肌血运重建在CCS患者的治疗中都起着核心作用。然而,由于CCS的异质性,在临床实践中确定哪些患者可能从经皮冠状动脉介入治疗(PCI)中获益是一项挑战。此外,PCI的重要性仍存在争议,尤其是在CCS患者中。因此,本综述结合当前的ESC指南和缺血性心脏病试验(医学与侵入性方法比较健康效果国际研究),讨论了CCS患者的诊断和治疗方法,以概述改善症状和预后的最佳策略。