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空气中铅源的接近与儿童生命前四年执行功能的降低有关。

Proximity to sources of airborne lead is associated with reductions in Children's executive function in the first four years of life.

机构信息

Department of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, 16802, USA.

Education and Workforce Development, RTI International, Washington, DC, 20005, USA.

出版信息

Health Place. 2021 Mar;68:102517. doi: 10.1016/j.healthplace.2021.102517. Epub 2021 Feb 2.

Abstract

Although policies to remove lead from gasoline have resulted in a substantial reduction in airborne lead, multiple industries are known to generate lead that is released in the air. The present study examines the extent to which residential proximity to a documented source of airborne lead is associated with intellectual and executive function in children. Data were available for n = 849 children from the Family Life Project. Geolocation for children's residences between birth and 36 months were referenced against the Environmental Protection Agency's Risk Screening Environmental Indicators (RSEI) database, which estimates exposure for each ½ mile grid in the contiguous United States. Instrumental variable models were employed to estimate causal associations between exposure and cognitive outcomes measured at 36, 48, and 60 months, using census-documented density of manufacturing employment as the instrument. Models of continuous lead dosage indicated small negative effects for both child IQ and executive function (EF). These results indicate that RSEI estimates of airborne lead exposure are meaningfully associated with decrements in cognitive development.

摘要

尽管从汽油中去除铅的政策已经导致空气中的铅含量大量减少,但已知多个行业会产生释放到空气中的铅。本研究考察了居住在有记录的空气传播铅源附近与儿童智力和执行功能之间的关系。家庭生活项目的 n=849 名儿童提供了数据。在出生到 36 个月期间,儿童住所的地理位置参考了美国环境保护署的风险筛选环境指标 (RSEI) 数据库,该数据库估计了美国大陆每个半英里网格的暴露情况。利用普查记录的制造业就业密度作为工具变量,采用工具变量模型估计了暴露与 36、48 和 60 个月时测量的认知结果之间的因果关系。连续剂量的铅模型表明,儿童智商和执行功能 (EF) 都出现了轻微的负效应。这些结果表明,RSEI 对空气传播铅暴露的估计与认知发展的下降有明显的关联。

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