口腔癌患者的口腔健康相关生活质量：系统评价和荟萃分析。

Oral health-related quality of life in oral cancer patients: systematic review and meta-analysis.

机构信息

Department of Oral & Maxillofacial Pathology, People's College of Dental Sciences & Research Centre, People's University, Bhopal, 462037, Madhya Pradesh, India.

Department of Oral Medicine & Radiology, Government Dental College & Hospital, Nagpur, 440009, Maharashtra, India.

出版信息

Future Oncol. 2021 Mar;17(8):979-990. doi: 10.2217/fon-2020-0881. Epub 2021 Feb 5.

DOI:10.2217/fon-2020-0881

PMID:33541115

Abstract

The purpose of this meta-analysis was to evaluate the impact of oral health on quality of life in oral cancer patients (OCPs). PubMed, Scopus and Web of Science databases were searched for publications on oral health-related quality of life (OHRQoL) in OCP and the information was extracted according to the PRISMA guidelines. A random effect model was used to obtain the pooled standard mean differences of Oral Health Impact Profile (OHIP)-14 questionnaire responses in meta-analysis. total of 12 research papers were analyzed and revealed poor OHRQoL in OCPs (standard mean difference: 2.53; 95% CI: 1.55-3.50; p < 0.00001) compared with healthy individuals due to the effects of oncotherapy. Moreover, OHRQoL deteriorated with combinations of different treatment modalities. Oral health and oncotherapy can affect the quality of life in OCPs.

摘要

本荟萃分析的目的是评估口腔健康对口腔癌患者（OCP）生活质量的影响。通过检索 PubMed、Scopus 和 Web of Science 数据库，获取有关 OCP 口腔健康相关生活质量（OHRQoL）的出版物，并根据 PRISMA 指南提取信息。采用随机效应模型获得荟萃分析中口腔健康影响量表（OHIP）-14 问卷应答的汇总标准均数差。对 12 篇研究论文进行了分析，结果表明由于肿瘤治疗的影响，OCP 患者的 OHRQoL 较差（标准均数差：2.53；95%CI：1.55-3.50；p<0.00001），与健康个体相比。此外，不同治疗方式的组合使 OHRQoL 恶化。口腔健康和肿瘤治疗都会影响 OCP 的生活质量。