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新生儿黄金时间:对澳大利亚和新西兰新生儿网络单位对极早产儿进行早期稳定化实践的调查。

Neonatal Golden Hour: A survey of Australian and New Zealand Neonatal Network units' early stabilisation practices for very preterm infants.

机构信息

Newborn Research Centre, Royal Women's Hospital, Melbourne, Victoria, Australia.

Department of Obstetrics and Gynaecology, The University of Melbourne, Melbourne, Victoria, Australia.

出版信息

J Paediatr Child Health. 2021 Jul;57(7):990-997. doi: 10.1111/jpc.15360. Epub 2021 Feb 5.

Abstract

AIM

To identify current 'Golden Hour' practices for initial stabilisation of very preterm infants <32 weeks' gestational age (GA) within tertiary neonatal intensive care units (NICUs) in the Australian and New Zealand Neonatal Network (ANZNN).

METHODS

A 76-question survey regarding delivery room (DR) and NICU stabilisation practices was distributed electronically to directors of tertiary perinatal NICUs in the ANZNN in January 2019. Responses were categorised into GA subgroups: 23-24, 25-27 and 28-31 weeks' GA.

RESULTS

The response rate was 100% (24/24 units). Delayed cord clamping (DCC) was practised 'always' or 'often' by 21 units (88%). All units used oximetry to target oxygen saturations, and 23/24 (96%) commenced resuscitation in <40% oxygen. Ten units (42%) routinely used DR electrocardiography monitoring. CPAP was preferred as primary respiratory support in one-third of units for infants born 23-24 weeks' GA, compared with 19 units (79%) at 25-27 weeks' GA and 23 units (96%) at 28-31 weeks' GA. DR skin-to-skin care was uncommon, particularly at lower GAs. Five units (21%) used minimally invasive surfactant therapy for non-intubated infants at 23-24 weeks' GA, 13 units (54%) at 25-27 weeks' GA and 16 units (67%) at 28-31 weeks' GA.

CONCLUSIONS

Most Golden Hour stabilisation practices align with international guidelines. Consistency exists with respect to DCC, oxygen saturation targeting and primary CPAP use for infants 25 weeks' GA and above. Where evidence is less certain, practices vary across ANZNN NICUs. Time targets for stabilisation measures may help standardise practice for this population.

摘要

目的

确定澳大利亚和新西兰新生儿网络(ANZNN)中三级新生儿重症监护病房(NICU)中初始稳定极早产儿(<32 周妊娠龄(GA))的当前“黄金时间”实践。

方法

2019 年 1 月,通过电子邮件向 ANZNN 中三级围产期 NICU 的主任分发了一份关于产房(DR)和 NICU 稳定实践的 76 个问题的调查。根据 GA 亚组对回复进行分类:23-24、25-27 和 28-31 周 GA。

结果

回复率为 100%(24/24 个单位)。21 个单位(88%)经常或经常进行延迟脐带夹闭(DCC)。所有单位均使用血氧饱和度仪来目标氧饱和度,并且 23/24(96%)在<40%的氧气下开始复苏。10 个单位(42%)常规进行 DR 心电图监测。CPAP 作为三分之一 23-24 周 GA 出生婴儿的主要呼吸支持,与 25-27 周 GA 的 19 个单位(79%)和 28-31 周 GA 的 23 个单位(96%)相比。DR 皮肤接触护理很少见,特别是在较低的 GA 下。5 个单位(21%)在 23-24 周 GA 的非插管婴儿中使用微创表面活性剂治疗,13 个单位(54%)在 25-27 周 GA 中,16 个单位(67%)在 28-31 周 GA 中。

结论

大多数黄金时间稳定化实践与国际指南一致。对于 25 周 GA 及以上的婴儿,DCC、氧饱和度目标和主要 CPAP 使用方面存在一致性。在证据不太确定的情况下,ANZNN NICU 之间的实践存在差异。稳定化措施的时间目标可能有助于为该人群标准化实践。

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