同步多灶性小管状腺瘤。
Synchronous Multifocal Canalicular Adenomas.
机构信息
School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA.
Department of Oral and Maxillofacial Surgery, Fiona Stanley Hospital, Murdoch, WA, Australia.
出版信息
Head Neck Pathol. 2021 Sep;15(3):945-949. doi: 10.1007/s12105-021-01293-w. Epub 2021 Feb 5.
Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.
管腺瘤（CAD）是一种罕见的良性小唾液腺肿瘤，好发于上唇黏膜。一位 80 岁女性因上唇黏膜和双侧颊黏膜的九个黏膜下结节就诊。组织病理学检查显示，在疏松的低细胞黏液样基质中存在多灶性界限清楚的肿瘤岛，呈管状生长模式。相互连接的柱状肿瘤细胞呈管腔状。除了特征性的组织病理学发现外，全面的免疫组织化学小组支持多灶性 CAD 的最终诊断。CAD 的同步多灶性是一种罕见的发现，本文通过临床病理相关性分析很好地例证了这种情况。
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