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在横断面数据中，多维功能健身评分与 2 型糖尿病的相关性强于肥胖参数。

A multidimensional functional fitness score has a stronger association with type 2 diabetes than obesity parameters in cross sectional data.

机构信息

BILD Clinic, Deenanath Mangeshkar Hospital, Pune, India.

Department of Psychology, University of Michigan, Ann Arbor, MI, United States of America.

出版信息

PLoS One. 2021 Feb 5;16(2):e0245093. doi: 10.1371/journal.pone.0245093. eCollection 2021.

DOI:10.1371/journal.pone.0245093
PMID:33544739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7864668/
Abstract

OBJECTIVES

We examine here the association of multidimensional functional fitness with type 2 diabetes mellitus (T2DM) as compared to anthropometric indices of obesity such as body mass index (BMI) and waist to hip ratio (WHR) in a sample of Indian population.

RESEARCH DESIGN AND METHOD

We analysed retrospective data of 663 volunteer participants (285 males and 378 females between age 28 and 84), from an exercise clinic in which every participant was required to undergo a health related physical fitness (HRPF) assessment consisting of 15 different tasks examining 8 different aspects of functional fitness.

RESULTS

The odds of being diabetic in the highest quartile of BMI were not significantly higher than that in the lowest quartile in either of the sexes. The odds of being a diabetic in the highest WHR quartile were significantly greater than the lowest quartile in females (OR = 4.54 (1.95, 10.61) as well as in males (OR = 3.81 (1.75, 8.3). In both sexes the odds of being a diabetic were significantly greater in the lowest quartile of HRPF score than the highest (males OR = 10.52 (4.21, 26.13); females OR = 10.50 (3.53, 31.35)). After removing confounding, the predictive power of HRPF was significantly greater than that of WHR. HRPF was negatively correlated with WHR, however for individuals that had contradicting HRPF and WHR based predictions, HRPF was the stronger predictor of T2DM.

CONCLUSION

The association of multidimensional functional fitness score with type 2 diabetes was significantly stronger than obesity parameters in a cross sectional self-selected sample from an Indian city.

摘要

目的

我们在此研究了多维功能体能与 2 型糖尿病（T2DM）的相关性，与身体质量指数（BMI）和腰臀比（WHR）等肥胖的人体测量学指标相比，在印度人群样本中。

研究设计与方法

我们分析了来自一个运动诊所的 663 名志愿者参与者（年龄在 28 至 84 岁之间，其中 285 名男性和 378 名女性）的回顾性数据，每个参与者都需要接受一项与健康相关的体能评估（HRPF），其中包括 15 项不同的任务，检查 8 个不同方面的功能体能。

结果

在男女两性中，BMI 最高四分位组的糖尿病患病几率都没有显著高于最低四分位组。在女性中，WHR 最高四分位组的糖尿病患病几率明显高于最低四分位组（OR=4.54（1.95，10.61）），在男性中也明显高于最低四分位组（OR=3.81（1.75，8.3））。在两性中，HRPF 得分最低四分位组的糖尿病患病几率都显著高于最高四分位组（男性 OR=10.52（4.21，26.13）；女性 OR=10.50（3.53，31.35））。在消除混杂因素后，HRPF 的预测能力明显大于 WHR。HRPF 与 WHR 呈负相关，但对于那些 HRPF 和 WHR 预测结果不一致的个体，HRPF 是 T2DM 的更强预测指标。

结论

在来自印度城市的横断面自我选择样本中，多维功能体能评分与 2 型糖尿病的相关性明显强于肥胖参数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/78a78f9b3716/pone.0245093.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/6e4e8f620dc3/pone.0245093.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/f32428f98a2f/pone.0245093.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/9c78d545a5b3/pone.0245093.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/6fbcef07ebfa/pone.0245093.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/78a78f9b3716/pone.0245093.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/6e4e8f620dc3/pone.0245093.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/f32428f98a2f/pone.0245093.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/9c78d545a5b3/pone.0245093.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/6fbcef07ebfa/pone.0245093.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f93/7864668/78a78f9b3716/pone.0245093.g005.jpg

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Fitness and Fatness as Health Markers through the Lifespan: An Overview of Current Knowledge.作为贯穿一生的健康指标的健康与肥胖：当前知识概述
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Level of obesity is directly associated with the clinical and functional consequences of knee osteoarthritis.肥胖程度与膝骨关节炎的临床和功能后果直接相关。
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