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乳酸钙和氟化物溶液漱口对诊室漂白过程中牙齿敏感性和颜色变化效果的影响:一项随机临床试验。

Influence of calcium lactate and fluoride solution mouthrinses on tooth sensitivity and effectiveness of color change during in-office bleaching: A randomized clinical trial.

机构信息

Faculdade São Leopoldo Mandic, Campinas, São Paulo, Brazil.

Faculdade São Leopoldo Mandic, Campinas, São Paulo, Brazil,

出版信息

Am J Dent. 2021 Feb;34(1):10-16.

PMID:33544983
Abstract

PURPOSE

To conduct a clinical evaluation of calcium lactate and sodium fluoride mouthrinses in reducing sensitivity and efficacy of color change during in-office bleaching.

METHODS

75 participants were selected and divided into three groups (n= 25), according to the type of desensitizing treatment tested: calcium lactate mouthrinse prior to sodium fluoride mouthrinse before each bleaching session; daily mouthrinse with sodium fluoride; control (absence of mouthrinse). Each mouthrinse was used for 1 minute. Bleaching was performed following the same protocol in all groups, with 40% hydrogen peroxide (Opalescence Boost), in three 40-minute sessions, with a 48-hour interval between sessions. Clinical parameters such as sensitivity, gingival irritation and mouthrinse acceptability were assessed using Visual Analogue Scale (VAS) and clinical examination at two timepoints: baseline (before any treatment) and 48 hours after the end of treatment. The color was evaluated with a spectrophotometer (VITA Classical scale guide, 3D Master guide and CIELab*). The data were analyzed by generalized linear models and by one-way ANOVA.

RESULTS

There was significant color change in all groups according to the VITA Classical scale guide (P< 0.001). There was no significant difference among the groups for ΔL*, Δa*, Δb* and ΔE over time (P> 0.05). The control group presented a significant increase in sensitivity (P= 0.008). The other groups showed no significant difference between initial and final timepoints (P> 0.05). No symptoms of gingival irritation were observed in any of the groups evaluated. All desensitizing treatments presented high acceptability. Bleaching treatment was effective, regardless of association with desensitizing treatments. No treatment prevented bleaching sensitivity, but the absence of a combined desensitizing treatment led to increased sensitivity.

CLINICAL SIGNIFICANCE

Although bleaching sensitivity during in-office bleaching treatment cannot be avoided, daily fluoridated mouthrinse or calcium lactate used prior to fluoridated mouthrinse prevented its increase.

摘要

目的

评估乳酸钙和氟化钠漱口液在减少诊室漂白过程中敏感性和颜色变化效果的临床效果。

方法

根据测试的脱敏治疗类型,将 75 名参与者分为三组(n=25):在每次漂白治疗前先用乳酸钙漱口,然后用氟化钠漱口;每天用氟化钠漱口;对照组(不漱口)。每种漱口液使用 1 分钟。所有组均按照相同的方案进行漂白,使用 40%双氧水(Opalescence Boost),分三次每次 40 分钟,每次治疗间隔 48 小时。使用视觉模拟量表(VAS)和临床检查评估临床参数,如敏感性、牙龈刺激和漱口液可接受性,在两个时间点进行评估:基线(任何治疗前)和治疗结束后 48 小时。使用分光光度计(VITA Classical 比色板指南、3D Master 比色板指南和 CIELab*)评估颜色。使用广义线性模型和单向方差分析对数据进行分析。

结果

根据 VITA Classical 比色板指南,所有组均出现明显的颜色变化(P<0.001)。随着时间的推移,各组之间的ΔL*、Δa*、Δb*和ΔE 无显著差异(P>0.05)。对照组敏感性显著增加(P=0.008)。其他组初始和最终时间点之间无显著差异(P>0.05)。评估的任何组均未观察到牙龈刺激的症状。所有脱敏治疗均具有较高的可接受性。漂白治疗有效,无论是否与脱敏治疗联合使用。没有治疗可以预防漂白敏感性,但缺乏联合脱敏治疗会导致敏感性增加。

临床意义

尽管在诊室漂白治疗期间无法避免漂白敏感性,但每天使用含氟漱口液或在使用含氟漱口液前使用乳酸钙可防止其增加。

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