Holmquist N D
Department of Pathology, LSUMC, New Orleans 70112.
Am J Clin Pathol. 1988 Apr;89(4):499-504. doi: 10.1093/ajcp/89.4.499.
This investigation was undertaken to determine the effectiveness of detecting urinary tract cancer in an outpatient population utilizing the urinalysis sediment. A total of 9870 urinalysis wet preparations was examined on patients from various clinics serviced by the clinical microscopy laboratories. One hundred forty-eight of these examinations were considered to be abnormal (1.5%). Follow-up urine specimens from the patients with atypical wet preparations examined in the cytology laboratory by the permanent procedure were obtained from 100 patients (68% return rate). Histopathologic follow-up studies revealed 12 of the original abnormal wet preparations had histologic evidence of cancer. Such a high pick up rate (1.2 per 1000) suggests that this examination for cancer is a valuable additional part of urinalysis.
本研究旨在确定利用尿液分析沉淀物在门诊人群中检测尿路癌症的有效性。临床显微镜实验室对来自各个诊所的患者共9870份尿液分析湿片进行了检查。其中148份检查被认为异常（1.5%）。对在细胞学实验室通过永久制片法检查的非典型湿片患者的随访尿液标本，从100名患者中获取（回收率68%）。组织病理学随访研究显示，最初148份异常湿片中，有12份有癌症的组织学证据。如此高的检出率（每1000人中有1.2人）表明，这种癌症检查是尿液分析中有价值的补充部分。
