Przykaza K, Jurak M, Wiącek A E, Mroczka R
Department of Interfacial Phenomena, Institute of Chemical Sciences, Faculty of Chemistry, University of Maria Curie-Skłodowska, Maria Curie-Skłodowska Sq. 3, 20031 Lublin, Poland.
Department of Interfacial Phenomena, Institute of Chemical Sciences, Faculty of Chemistry, University of Maria Curie-Skłodowska, Maria Curie-Skłodowska Sq. 3, 20031 Lublin, Poland.
Mater Sci Eng C Mater Biol Appl. 2021 Jan;120:111658. doi: 10.1016/j.msec.2020.111658. Epub 2020 Oct 20.
In this paper, we propose a method of obtaining multi-component surface coatings on PEEK polymer, which is becoming increasingly interested in a very wide branch of medicine - orthopedics. Thanks to the plasma techniques used and due to the presence of chitosan, the materials obtained are characterized by sterility, antisepticity, can accelerate wound healing, and serve as a drug delivery system directly to the tissues in need. In addition, the use of ternary Langmuir-Blodgett (lipid-sterol, peptide) films has resulted in significant change of surfaces polarity. The physico-chemical properties of the ternary Langmuir films obtained on the water subphase were tested exploiting Langmuir trough and a Brewster angle microscope. Then they were transferred to the modified surfaces of the solid PEEK polymer, where changes in wettability as well as surface free energy were determined by the type of substrate/coating and the hybrid composition. Additionally, surface chemistry was studied applying time of flight secondary ion mass spectrometry.
在本文中，我们提出了一种在聚醚醚酮（PEEK）聚合物上获得多组分表面涂层的方法，聚醚醚酮在医学的一个非常广泛的分支——骨科中越来越受到关注。由于所使用的等离子体技术以及壳聚糖的存在，所获得的材料具有无菌、防腐的特性，能够加速伤口愈合，并可作为直接向需要的组织输送药物的系统。此外，三元朗缪尔-布洛杰特（脂质-甾醇、肽）膜的使用导致了表面极性的显著变化。利用朗缪尔槽和布鲁斯特角显微镜测试了在水亚相上获得的三元朗缪尔膜的物理化学性质。然后将它们转移到固体PEEK聚合物的改性表面上，在那里根据基材/涂层的类型和混合成分确定润湿性以及表面自由能的变化。此外，应用飞行时间二次离子质谱法研究了表面化学。
