Department of Radiology. The Fourth People's Hospital of Taizhou, Taizhou.
Department of Interventional Radiology, Jiangyin People's Hospital, Jiangyin.
Medicine (Baltimore). 2021 Jan 22;100(3):e23938. doi: 10.1097/MD.0000000000023938.
This study was designed as a means of comparing the clinical efficacy and long-term outcomes of covered vs bare stent insertion as a treatment for distal malignant biliary obstruction (DMBO) caused by primary common biliary cancer (PCBC).This retrospective study was designed using data collected between January 2012 and December 2019 to assess the short- and long-term outcomes in patients with DMBO caused by PCBC treated by inserting either bare or covered stents were compared.Ninety two patients with DMBO caused by PCBC were divided between bare (n = 51) or covered (n = 41) stent groups. Technical success rates in both groups were 100%. Clinical success of bare vs covered stent use were 96.1% and 97.6% (P = 1.00). Stent dysfunction was seen in 17 and 6 patients in the bare and covered stent groups, respectively (P = .04). The median stent patency for bare and covered stents was 177 and 195 days, respectively (P = .51). The median survival was 188 and 200 days in the bare and covered stent groups, respectively (P = .85).For patients with DMBO caused by PCBC, using bare vs covered stents yields similar clinical efficacy and long term outcomes.
本研究旨在比较覆盖支架与裸支架置入治疗原发性胆管癌(PCBC)所致远端恶性胆道梗阻(DMBO)的临床疗效和长期结局。本回顾性研究采用 2012 年 1 月至 2019 年 12 月期间收集的数据设计,评估了 PCBC 所致 DMBO 患者接受裸支架或覆盖支架置入治疗的短期和长期结局。92 例 PCBC 所致 DMBO 患者分为裸支架(n=51)或覆盖支架(n=41)组。两组技术成功率均为 100%。裸支架与覆盖支架组的临床成功率分别为 96.1%和 97.6%(P=1.00)。裸支架和覆盖支架组分别有 17 例和 6 例患者出现支架功能障碍(P=0.04)。裸支架和覆盖支架的中位支架通畅时间分别为 177 天和 195 天(P=0.51)。裸支架和覆盖支架组的中位生存时间分别为 188 天和 200 天(P=0.85)。对于 PCBC 所致 DMBO 患者,使用裸支架与覆盖支架的临床疗效和长期结局相似。