NorthShore University HealthSystem, 2650 Ridge Ave., Walgreen Suite 2507, Evanston, IL, 60201, USA.
NorthShore University HealthSystem, 2650 Ridge Ave., Walgreen Suite 2507, Evanston, IL, 60201, USA.
Am J Surg. 2021 Mar;221(3):534-537. doi: 10.1016/j.amjsurg.2020.12.048. Epub 2021 Jan 11.
Scarring and disrupted tissue planes add to already-complex neck anatomy and make localization of nonpalpable pathology difficult in cervical endocrine reoperations. We describe the use of radioactive iodine-125 seed localization (RSL) in 6 patients with metastatic papillary thyroid carcinoma (PTC) and 2 with recurrent hyperparathyroidism.
Eight patients had 2-D ultrasound-guided RSL of the target lesion, 0-3 days preoperatively. Intraoperative gamma probe (Neoprobe) was used to plan incision placement and localize the implanted seed. Recorded operative variables included: number of lymph nodes (LNs) harvested, estimated blood loss (EBL), operative time, length of stay (LOS) and RSL and operative complications.
All patients had successful resection of the targeted area and removal of the radioactive seed. There was no seed migration. Two complications occurred in the thyroid group.
Radioactive iodine 125 seeds facilitate successful localization of endocrine pathology during reoperative cervical procedures.
瘢痕和组织平面的破坏增加了原本就复杂的颈部解剖结构，使难以定位不可触及的颈部内分泌手术中的病变。我们描述了放射性碘-125 种子定位（RSL）在 6 例转移性甲状腺乳头状癌（PTC）和 2 例复发性甲状旁腺功能亢进患者中的应用。
8 例患者在术前 0-3 天进行了二维超声引导的 RSL 定位靶病变。术中使用伽马探针（Neoprobe）来规划切口位置并定位植入的种子。记录的手术变量包括：淋巴结（LNs）清扫数量、估计出血量（EBL）、手术时间、住院时间（LOS）、RSL 和手术并发症。
所有患者均成功切除了目标区域并取出了放射性种子。没有种子迁移。甲状腺组有 2 例并发症。
放射性碘 125 种子有助于在颈部内分泌手术的再次手术中成功定位内分泌病变。
