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青少年哮喘患者的心理健康和整体健康状况:预防和发生哮喘和尘螨过敏的出生队列研究。

Mental Well-being and General Health in Adolescents with Asthma: The Prevention and Incidence of Asthma and Mite Allergy Birth Cohort Study.

机构信息

Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

出版信息

J Pediatr. 2021 Jun;233:198-205.e2. doi: 10.1016/j.jpeds.2021.01.074. Epub 2021 Feb 4.

Abstract

OBJECTIVES

To assess whether adolescents with asthma experience a lower mental well-being and lower general health than their peers without asthma.

STUDY DESIGN

Data from the Prevention and Incidence of Asthma and Mite Allergy study were used. At the ages of 11, 14, 17, and 20 years, 2651, 2522, 2094, and 2206 participants, respectively, completed questionnaires. Their parents completed questionnaires at the ages of 11 (n = 2660), 14 (n = 2338), and 17 years (n = 1872). Asthma was defined according to the Mechanisms of the Development of Allergy criteria. Mental well-being was measured using the Mental Health Index-5 and was reported by the adolescents. General health, measured on a 4-point Likert scale, was reported by the adolescents and their parents. We estimated associations of asthma with mental well-being and perceived general health using generalized estimating equations.

RESULTS

At ages 11, 14, 17, and 20 years, 6.7%, 6.9%, 5.0%, and 6.6%, respectively, of the adolescents had asthma. Adolescents with asthma did not score differently on the Mental Health Index than their peers without asthma. Adolescents with asthma were less likely to experience good or excellent health than their peers without asthma (aOR, 0.37; 95% CI, 0.26-0.51 for intermittent asthma and 0.33; 95% CI, 0.25-0.41 for persistent asthma). These results remain similar across the different ages.

CONCLUSIONS

The mental well-being of adolescents with asthma is similar to that of their peers without asthma, although adolescents with asthma are less likely to perceive a good or excellent general health.

摘要

目的

评估哮喘青少年的心理健康和总体健康状况是否低于无哮喘的同龄人。

研究设计

使用预防和发生哮喘及螨变应性研究的数据。在 11、14、17 和 20 岁时,分别有 2651、2522、2094 和 2206 名参与者完成了问卷。他们的父母分别在 11(n=2660)、14(n=2338)和 17 岁(n=1872)时完成了问卷。哮喘根据过敏发病机制标准定义。心理健康采用心理健康指数-5 进行衡量,由青少年报告。总体健康状况采用 4 级 Likert 量表衡量,由青少年及其父母报告。我们使用广义估计方程估计哮喘与心理健康和感知总体健康之间的关联。

结果

在 11、14、17 和 20 岁时,分别有 6.7%、6.9%、5.0%和 6.6%的青少年患有哮喘。患有哮喘的青少年在心理健康指数上的得分与没有哮喘的同龄人没有差异。与没有哮喘的同龄人相比,患有哮喘的青少年更有可能体验到健康状况不佳或较差(aOR,0.37;95%CI,0.26-0.51 为间歇性哮喘,0.33;95%CI,0.25-0.41 为持续性哮喘)。这些结果在不同年龄组中仍然相似。

结论

哮喘青少年的心理健康状况与无哮喘的同龄人相似,尽管哮喘青少年更有可能认为自己的总体健康状况不佳或较差。

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