Hameed N U Farrukh, Zhao Zehao, Zhang Jie, Bu Linghao, Zhou Yuyao, Jin Lei, Bai Hongmin, Li Weiping, Tang Jie, Lu Junfeng, Wu Jinsong, Mao Ying
Department of Neurological Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Brain Function Laboratory, Neurosurgical Institute of Fudan University, Shanghai, China.
Oper Neurosurg (Hagerstown). 2021 Apr 15;20(5):477-483. doi: 10.1093/ons/opaa476.
To be efficient, intraoperative task-presentation systems must accurately present various language and cognitive tasks to patients undergoing awake surgery, and record behavioral data without compromising convenience of surgery.
To present an integrated brain mapping task-presentation system we developed and evaluate its effectiveness in intraoperative task presentation.
The Brain Mapping Interactive Stimulation System (Brain MISS) is a flexible task presentation system that adjusts for patient comfort, needs of the surgeon, and operating team, with multivideo recording for patients' behavior. A total of 48 patients from 3 centers underwent intraoperative language task test during awake brain surgery with the Brain MISS. Each patient was assigned 5 questions each on picture naming, reading, and listening comprehension before and during awake surgeries. The accuracy of intraoperative stimulus-response (without electrical stimulation) was recorded. The Brain MISS was to be considered effective, if the lower limit of 95% CI of patients' intraoperative response was ≥80% and also if the accuracy of intraoperative response of all patients was statistically higher than 80%.
All patients successfully underwent intraoperative assessment with the Brain MISS. The overall accuracy of stimulus response was 95.8% (95% CI 90.18%-100.00%), with the lower limit being higher than 80% and the response accuracy also significantly being higher than 80% in all patients (P = .006).
The Brain MISS is a portable and effective system for presenting and streamlining complicated language and cognitive tasks during awake surgery. It can also record standardized patient response data for neuroscientific research.
为提高效率，术中任务呈现系统必须向接受清醒手术的患者准确呈现各种语言和认知任务，并记录行为数据，同时不影响手术的便利性。
介绍我们开发的一种集成式脑图谱任务呈现系统，并评估其在术中任务呈现方面的有效性。
脑图谱交互式刺激系统（Brain MISS）是一种灵活的任务呈现系统，可根据患者舒适度、外科医生和手术团队的需求进行调整，并对患者行为进行多视频记录。来自3个中心的48例患者在清醒脑手术期间使用Brain MISS进行术中语言任务测试。在清醒手术前和手术期间，为每位患者分配5道关于图片命名、阅读和听力理解的问题。记录术中刺激-反应（无电刺激）的准确性。如果患者术中反应的95%置信区间下限≥80%，并且所有患者的术中反应准确性在统计学上高于80%，则认为Brain MISS有效。
所有患者均使用Brain MISS成功完成术中评估。刺激反应的总体准确率为95.8%（95%置信区间90.18%-100.00%），下限高于80%，且所有患者的反应准确率在统计学上也显著高于80%（P = 0.006）。
Brain MISS是一种便携式有效系统，可在清醒手术期间呈现和简化复杂的语言和认知任务。它还可为神经科学研究记录标准化的患者反应数据。
