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使用东莨菪碱透皮贴剂减少唾液分泌。

Reduction of salivary flow with Scopoderm TTS.

作者信息

Talmi Y P, Finkelstein Y, Zohar Y, Laurian N

机构信息

Department of Otolaryngology, Golda Medical Center, Hasharon Hospital, Petah-Tiqva, Israel.

出版信息

Ann Otol Rhinol Laryngol. 1988 Mar-Apr;97(2 Pt 1):128-30. doi: 10.1177/000348948809700206.

DOI:10.1177/000348948809700206
PMID:3355042
Abstract

Scopoderm transdermal therapeutic system (TTS) is a form of application permitting programmed release of scopolamine through the skin into the bloodstream. Scopoderm TTS is indicated for prevention of nausea and vomiting associated with motion sickness. The most common side effect associated with its use is dryness of the mouth. We have been using Scopoderm TTS for reducing salivary flow in patients with sialorrhea or with difficulties in swallowing normal amounts of salivary secretions. Good results were achieved with minimal discomfort from adverse effects. We recommend the use of Scopoderm TTS in selected cases of sialorrhea and drooling, preoperatively and postoperatively in patients undergoing surgery of oral, laryngeal, and pharyngeal lesions.

摘要

东莨菪碱透皮治疗系统(TTS)是一种给药形式,可使东莨菪碱通过皮肤编程释放进入血液循环。东莨菪碱透皮治疗系统适用于预防晕动病相关的恶心和呕吐。使用该药物最常见的副作用是口干。我们一直在使用东莨菪碱透皮治疗系统来减少流涎或吞咽正常量唾液分泌物有困难患者的唾液分泌。在不良反应引起的不适最小的情况下取得了良好效果。我们建议在某些流涎和流口水的病例中,以及在口腔、喉部和咽部病变手术患者的术前和术后使用东莨菪碱透皮治疗系统。

相似文献

1
Reduction of salivary flow with Scopoderm TTS.使用东莨菪碱透皮贴剂减少唾液分泌。
Ann Otol Rhinol Laryngol. 1988 Mar-Apr;97(2 Pt 1):128-30. doi: 10.1177/000348948809700206.
2
Reduction of salivary flow with transdermal scopolamine: a four-year experience.
Otolaryngol Head Neck Surg. 1990 Oct;103(4):615-8. doi: 10.1177/019459989010300415.
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Transdermal scopolamine use for post-rhytidectomy sialocele.透皮东莨菪碱用于除皱术后涎囊肿。
Aesthetic Plast Surg. 2004 Jan-Feb;28(1):24-8. doi: 10.1007/s00266-004-3115-5. Epub 2004 May 3.
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[Medicamental reduction of salivation with a plaster containing scopolamine in restorative prosthetics].[在修复性修复术中使用含东莨菪碱的膏药进行药物性减少唾液分泌]
Dtsch Zahnarztl Z. 1989 Sep;44(9):722-3.
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Transdermal scopolamine for prevention of motion sickness : clinical pharmacokinetics and therapeutic applications.用于预防晕动病的透皮东莨菪碱:临床药代动力学及治疗应用
Clin Pharmacokinet. 2006;45(6):543-66. doi: 10.2165/00003088-200645060-00001.
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Transdermal scopolamine in drooling.用于流涎的透皮东莨菪碱
J Ment Defic Res. 1988 Jun;32 ( Pt 3):233-7. doi: 10.1111/j.1365-2788.1988.tb01409.x.
7
Reduction of salivary flow in amyotrophic lateral sclerosis with Scopoderm TTS.使用东莨菪碱透皮贴剂减少肌萎缩侧索硬化症患者的唾液分泌
Head Neck. 1989 Nov-Dec;11(6):565. doi: 10.1002/hed.2880110617.
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Control of drooling using transdermal scopolamine skin patches. A case report.使用透皮东莨菪碱贴片控制流涎。病例报告。
Med Oral Patol Oral Cir Bucal. 2008 Jan 1;13(1):E27-30.
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[Effects and side effects of transdermal scopolamine for premedication in general anesthesia in elderly patients].[东莨菪碱透皮贴剂用于老年患者全身麻醉术前用药的效果及副作用]
Anasth Intensivther Notfallmed. 1986 Dec;21(6):301-6.
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[Transdermal therapeutic system of scopolamine (TTS-S) in the prevention of sea sickness and its mechanism of action].东莨菪碱经皮治疗系统(TTS-S)预防晕船及其作用机制
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1990 Oct;25(5):299-302, 319.

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Long-term scopolamine treatment and dental caries.长期东莨菪碱治疗与龋齿。
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Salivary gland diseases in children.儿童唾液腺疾病
GMS Curr Top Otorhinolaryngol Head Neck Surg. 2014 Dec 1;13:Doc06. doi: 10.3205/cto000109. eCollection 2014.
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Management of drooling in disabled patients with scopolamine patches.东莨菪碱贴片治疗残疾患者流涎的管理。
Br J Clin Pharmacol. 2010 Jun;69(6):684-8. doi: 10.1111/j.1365-2125.2010.03659.x.
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Nonsurgical treatment of drooling in a patient with closed head injury and severe dysarthria.闭合性颅脑损伤合并严重构音障碍患者流涎的非手术治疗
Dysphagia. 1991;6(1):40-9. doi: 10.1007/BF02503462.