Faculty of Chemistry, Shahid Beheshti University, G. C., P.O. Box 1983963113, Evin, Tehran, Islamic Republic of Iran.
Mikrochim Acta. 2021 Feb 6;188(3):73. doi: 10.1007/s00604-021-04727-y.
Gelatin microsphere-coated FeO@graphene quantum dots (FeO@GQD@GM) were designed and synthesized as a novel sorbent via ultrasonic-assisted dispersive magnetic solid-phase extraction (UA-DMSPE) method. The synthesized sorbent was identified and confirmed by FT-IR, XRD, VSM, and SEM techniques. UA-DMSPE was combined with corona discharge ion mobility spectrometry for trace determination of desipramine, sertraline, and citalopram. Effective parameters were considered and optimized. The proposed method, under optimal conditions, showed excellent linearity in different concentration ranges (2-700 ng mL, R > 0.995), repeatability (RSD < 5.1%), good sensitivity (LODs in the range 0.6-1.5 ng mL), high preconcentration factor (PF = 207-218), and acceptable relative recoveries (93.5-101.8%). Eventually, this method was used to determine tricyclic antidepressants in various biological samples. Schematic presentation of the microextraction and monitoring of TCAs by ultrasonic-assisted dispersive magnetic solid phase microextraction-ion mobility spectrometry producer.
通过超声辅助分散磁固相萃取（UA-DMSPE）方法，设计并合成了一种新型的胶态金微球包裹的 FeO@石墨烯量子点（FeO@GQD@GM）作为吸附剂。通过傅里叶变换红外光谱（FT-IR）、X 射线衍射（XRD）、振动样品磁强计（VSM）和扫描电子显微镜（SEM）技术对合成的吸附剂进行了鉴定和确认。将 UA-DMSPE 与电晕放电离子淌度谱法相结合，用于痕量测定去甲丙咪嗪、舍曲林和西酞普兰。考虑并优化了有效参数。在最佳条件下，该方法在不同浓度范围内（2-700ng mL，R>0.995）具有优异的线性、重复性（RSD<5.1%）、良好的灵敏度（LOD 在 0.6-1.5ng mL 范围内）、高富集因子（PF=207-218）和可接受的相对回收率（93.5-101.8%）。最终，该方法用于测定各种生物样品中的三环类抗抑郁药。通过超声辅助分散磁固相微萃取-离子淌度谱法监测 TCA 的示意图。
