• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

急性双侧足下垂伴或不伴马尾综合征:病例系列研究。

Acute bilateral foot drop with or without cauda equina syndrome-a case series.

机构信息

Department of Neurosurgery, New Royal Infirmary, Edinburgh, UK.

Department of Neurosurgery, King's College Hospital, London, UK.

出版信息

Acta Neurochir (Wien). 2021 Apr;163(4):1191-1198. doi: 10.1007/s00701-021-04735-0. Epub 2021 Feb 7.

DOI:10.1007/s00701-021-04735-0
PMID:33550516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7966217/
Abstract

INTRODUCTION

Isolated acute bilateral foot drop due to degenerative spine disease is an extremely rare neurosurgical presentation, whilst the literature is rich with accounts of chronic bilateral foot drop occurring as a sequela of systemic illnesses. We present, to our knowledge, the largest case series of acute bilateral foot drop, with trauma and relevant systemic illness excluded.

METHODS

Data from three different centres had been collected at the time of historic treatment, and records were subsequently reviewed retrospectively, documenting the clinical presentation, radiological level of compression, timing of surgery, and degree of neurological recovery.

RESULTS

Seven patients are presented. The mean age at presentation was 52.1 years (range 41-66). All patients but one were male. All had a painful radiculopathic presentation. Relevant discopathy was observed from L2/3 to L5/S1, the commonest level being L3/4. Five were treated within 24 h of presentation, and two within 48 h. Three had concomitant cauda equina syndrome; of these, the first two made a full motor recovery, one by 6 weeks follow-up and the second on the same-day post-op evaluation. Overall, five out of seven cases had full resolution of their ankle dorsiflexion pareses. One patient with 1/5 power has not improved. Another with 1/5 weakness improved to normal on the one side and to 3/5 on the other.

CONCLUSION

When bilateral foot drop occurs acutely, we encourage the consideration of degenerative spinal disease. Relevant discopathy was observed from L2/3 to L5/S1; aberrant innervation may be at play. Cauda equina syndrome is not necessarily associated with acute bilateral foot drop. The prognosis seems to be pretty good with respect to recovery of the foot drop, especially if partial at presentation and if treated within 48 h.

摘要

简介

孤立性急性双侧足下垂由于退行性脊柱疾病是一种极其罕见的神经外科表现,而文献中充满了慢性双侧足下垂作为全身疾病后遗症的报道。我们提出了,据我们所知,最大的急性双侧足下垂病例系列,排除了创伤和相关的全身疾病。

方法

在历史治疗时收集了来自三个不同中心的数据,随后回顾性地审查了记录,记录了临床表现、压迫的放射学水平、手术时机和神经恢复程度。

结果

提出了 7 例患者。发病时的平均年龄为 52.1 岁(范围 41-66 岁)。除 1 例外,所有患者均为男性。所有患者均表现为疼痛性神经根病。观察到从 L2/3 到 L5/S1 的相关椎间盘病,最常见的水平为 L3/4。5 例在发病后 24 小时内接受治疗,2 例在 48 小时内接受治疗。3 例伴有马尾综合征;其中前 2 例完全恢复运动功能,1 例在 6 周随访时,另 1 例在术后当天评估时。总体而言,7 例中有 5 例完全解决了踝背屈无力。1 例 1/5 肌力的患者没有改善。另 1 例 1/5 肌力的患者在一侧改善至正常,另一侧改善至 3/5。

结论

当双侧足下垂急性发作时,我们鼓励考虑退行性脊柱疾病。观察到从 L2/3 到 L5/S1 的相关椎间盘病;异常神经支配可能起作用。马尾综合征不一定与急性双侧足下垂相关。如果部分表现且在 48 小时内治疗,足下垂的恢复预后似乎相当好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81f5/7966217/6bf120282c37/701_2021_4735_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81f5/7966217/6a267d183dda/701_2021_4735_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81f5/7966217/6bf120282c37/701_2021_4735_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81f5/7966217/6a267d183dda/701_2021_4735_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81f5/7966217/6bf120282c37/701_2021_4735_Fig2_HTML.jpg

相似文献

1
Acute bilateral foot drop with or without cauda equina syndrome-a case series.急性双侧足下垂伴或不伴马尾综合征:病例系列研究。
Acta Neurochir (Wien). 2021 Apr;163(4):1191-1198. doi: 10.1007/s00701-021-04735-0. Epub 2021 Feb 7.
2
Acute bilateral foot drop due to lumbar disc herniation treated by bilateral interlaminar approach: case report and literature review.双侧腰椎间盘突出症致急性双侧足下垂:病例报告及文献复习。
Br J Neurosurg. 2023 Aug;37(4):899-901. doi: 10.1080/02688697.2020.1713992. Epub 2020 Jan 20.
3
Atypical Cauda Equina Syndrome with Lower Limb Clonus: A Literature Review and Case Report.不典型马尾综合征伴下肢阵挛:文献回顾与病例报告。
World Neurosurg. 2020 Feb;134:507-509. doi: 10.1016/j.wneu.2019.10.198. Epub 2019 Nov 9.
4
Acute Bilateral Isolated Foot Drop: Changing the Paradigm in Management of Degenerative Spine Surgery with Percutaneous Endoscopy.急性双侧孤立性足下垂:经皮内镜改变退行性脊柱手术管理模式
World Neurosurg. 2018 Feb;110:319-322. doi: 10.1016/j.wneu.2017.11.128. Epub 2017 Nov 28.
5
L1/2 Intradural Disc Herniation with Compression of the Proximal Cauda Equina Nerves: A Surgical Challenge.L1/2 硬脊膜内椎间盘疝,伴有近端马尾神经受压:手术挑战。
World Neurosurg. 2020 Oct;142:147-151. doi: 10.1016/j.wneu.2020.06.163. Epub 2020 Jun 27.
6
A Case Series of Acute Painless Bilateral Foot Drop Without Cauda Equina Syndrome.一组无马尾综合征的急性无痛性双侧足下垂病例系列
J Orthop Case Rep. 2021 Oct;11(10):13-16. doi: 10.13107/jocr.2021.v11.i10.2446.
7
Prognosis for Recovery of Foot Drop after Transforaminal Endoscopic Decompression of Far Lateral Lumbar 5-Sacral 1 Herniated Disc: Case Series.经椎间孔内窥镜减压治疗远外侧腰椎 5-骶 1 椎间盘突出症后足下垂恢复的预后:病例系列。
Pain Physician. 2019 Mar;22(2):E97-E103.
8
Long-term results and predictors of postoperative outcomes in patients with cauda equina syndrome following degenerative lumbar spine disease.退变性腰椎疾病致马尾综合征患者的术后结局及其影响因素的长期随访结果
Zh Vopr Neirokhir Im N N Burdenko. 2023;87(1):35-43. doi: 10.17116/neiro20238701135.
9
Acute bilateral isolated foot drop: Report of two cases.急性双侧孤立性足下垂:两例报告。
Asian J Neurosurg. 2015 Apr-Jun;10(2):123-5. doi: 10.4103/1793-5482.144596.
10
Does a history of lumbar spine surgery predict radiological cauda equina compression in patients undergoing MRI for suspected cauda equina syndrome?对于因疑似马尾综合征而接受MRI检查的患者,腰椎手术史能否预测影像学上的马尾神经受压情况?
Br J Neurosurg. 2020 Feb;34(1):76-79. doi: 10.1080/02688697.2019.1687845. Epub 2019 Nov 13.

引用本文的文献

1
Characterizing Spinal Decompression for Foot Drop Caused by Lumbar Degenerative Disease: A Systematic Review and Meta-Analysis of Cohorts.腰椎退行性疾病所致足下垂的脊髓减压特征:队列研究的系统评价与荟萃分析
J Clin Med. 2025 Jun 24;14(13):4470. doi: 10.3390/jcm14134470.
2
Hereditary Neuropathy with Liability to Pressure Palsy Presenting as Bilateral Foot Drop.表现为双侧足下垂的遗传性压力易感性周围神经病
Eurasian J Med. 2023 Feb;55(1):90-92. doi: 10.5152/eurasianjmed.2023.21154.
3
Evaluating Acute Bilateral Foot Drop: A Case Report.

本文引用的文献

1
Neurological function following early versus delayed decompression surgery for drop foot caused by lumbar degenerative diseases.腰椎退行性疾病导致足下垂患者行早期与延迟减压手术治疗后神经功能的比较。
J Clin Neurosci. 2020 Feb;72:39-42. doi: 10.1016/j.jocn.2020.01.039. Epub 2020 Jan 23.
2
Traumatic haemorrhagic lumbar synovial facet cyst presenting as bilateral foot drop: a case report.创伤性出血性腰椎滑膜小关节囊肿表现为双侧足下垂:一例报告
N Z Med J. 2018 Jul 13;131(1478):62-64.
3
Bilateral common peroneal nerve palsy following cardiac surgery.
评估急性双侧足下垂:一例报告
Cureus. 2022 Dec 21;14(12):e32794. doi: 10.7759/cureus.32794. eCollection 2022 Dec.
心脏手术后双侧腓总神经麻痹
Anadolu Kardiyol Derg. 2008 Aug;8(4):313-4.
4
Sudden bilateral foot drop: an unusual presentation of lumbar disc prolapse.突发双侧足下垂:腰椎间盘突出症的一种罕见表现。
Neurol India. 2003 Mar;51(1):71-2.